Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 17/20 | 0.67 |
| ▸ | RARG | P13631 | 17/20 | 0.67 |
| ▸ | RARA | P10276 | 14/20 | 0.67 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.50 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 4/20 | 0.45 |
| ▸ | RXRB | P28702 | 3/20 | 0.45 |
| ▸ | RXRG | P48443 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358183 | 1.00 | RARB (0.67) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8657242 | 0.83 | RARA (0.50) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL3453631 | 0.81 | RARB (1.00) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL31266609 | 0.81 | RARB (1.00) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8658266 | 0.78 | RARB (0.65) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL6378961 | 0.78 | RARB (0.61) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL5846371 | 0.78 | RARB (0.65) | RARBRARGRARARXRARXRB | |
| SCHEMBL8657215 | 0.76 | MEN1 (0.72) | RARBRARGRARA | |
| SCHEMBL9374463 | 0.75 | RARA (0.90) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8659574 | 0.75 | RARB (0.63) | RARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220016148-A1 | RETINOIC ACID RECEPTOR GAMMA AGONISTS TO ATTENUATE ANTHRACYCLINE-INDUCED CARDIOTOXICITY | NORTHWESTERN UNIVERSITY | 2022-01-20 | — | — | US | claimed |
| EP-0658553-B1 | Polycyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | CIRD GALDERMA (FR) | 1998-11-04 | — | — | EP | claimed |
| US-5723499-A | Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | C.I.R.D. GALDERMA (FR) | 1998-03-03 | — | — | US | claimed |
| EP-0658553-A1 | Polycyclic aromatic compounds, pharmaceutical compositions containing them and uses thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1995-06-21 | — | — | EP | claimed |
| US-12529032-B2 | Methods and culture substrates for controlled induction of biomimetic neural tissues comprising singular rosette structures | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2026-01-20 | — | — | US | disclosed |
| US-20250345316-A1 | METHODS OF INCREASING LYMPHOCYTE TRAFFICKING TO THE COLON BY STIMULATING RETINOIC ACID RECEPTORS AND ARYL HYDROCARBON RECEPTORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-11-13 | — | — | US | disclosed |
| WO-2025135136-A1 | METHOD FOR PRODUCING NAIL MATRIX CELLS | 学校法人関西医科大学 | 2025-06-26 | — | — | WO | disclosed |
| US-20240400983-A1 | CELL AGGREGATE INCLUDING PITUITARY HORMONE-PRODUCING CELLS AND METHOD FOR PRODUCING SAME | Sumitomo Pharma Co., Ltd. (JP) | 2024-12-05 | — | — | US | disclosed |
| US-20240392241-A1 | METHOD FOR PRODUCING CELL MASS INCLUDING PITUITARY TISSUE AND CELL MASS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-11-28 | — | — | US | disclosed |
| WO-2024171957-A1 | TRANSPLANTATION OF PITUITARY HORMONE-PRODUCING CELLS | 国立大学法人東海国立大学機構 | 2024-08-22 | — | — | WO | disclosed |
| EP-4410963-A1 | METHOD FOR PRODUCING CELL MASS INCLUDING PITUITARY TISSUE AND CELL MASS | Sumitomo Chemical Company, Limited (JP) | 2024-08-07 | — | — | EP | disclosed |
| EP-4410962-A1 | CELL AGGREGATE INCLUDING PITUITARY HORMONE-PRODUCING CELLS AND METHOD FOR PRODUCING SAME | Sumitomo Pharma Co., Ltd. (JP) | 2024-08-07 | — | — | EP | disclosed |
| US-20190024046-A1 | METHODS AND CULTURE SUBSTRATES FOR CONTROLLED INDUCTION OF BIOMIMETIC NEURAL TISSUES COMPRISING SINGULAR ROSETTE STRUCTURES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-01-24 | — | — | US | disclosed |
| EP-3393481-A1 | OIL-IN-WATER EMULSIONS INCLUDING RETINOIC ACID | NOVARTIS AG (CH) | 2018-10-31 | — | — | EP | disclosed |
| WO-2017192606-A1 | METHODS OF PRODUCING SPECIALIZED CARDIO-LIKE CELLS FROM STEM CELL | EMORY UNIVERSITY (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017108902-A1 | OIL-IN-WATER EMULSIONS INCLUDING RETINOIC ACID | NOVARTIS AG (CH) | 2017-06-29 | — | — | WO | disclosed |
| US-20160068806-A1 | COMPOSITIONS AND METHODS FOR PRECISE PATTERNING OF POSTERIOR NEUROECTODERM FROM HUMAN PLURIPOTENT STEM CELLS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2016-03-10 | — | — | US | disclosed |
| EP-0658553-B1 | Polycyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | CIRD GALDERMA (FR) | 1998-11-04 | — | — | EP | disclosed |
| US-5723499-A | Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | C.I.R.D. GALDERMA (FR) | 1998-03-03 | — | — | US | disclosed |
| EP-0658553-A1 | Polycyclic aromatic compounds, pharmaceutical compositions containing them and uses thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1995-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529032-B2 | Methods and culture substrates for controlled induction of biomimetic neural tissues comprising singular rosette structures | NES, CDH1, SHH | RARB 24/4885RARG 54/4885RARA 57/4885 |
| US-20220016148-A1 | RETINOIC ACID RECEPTOR GAMMA AGONISTS TO ATTENUATE ANTHRACYCLINE-INDUCED CARDIOTOXICITY | RARG, RXRG, RARA | RARB 4/4885RARG 1/4885RARA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.