Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 9/20 | 0.50 |
| ▸ | RARB | P10826 | 9/20 | 0.50 |
| ▸ | RARG | P13631 | 5/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358183 | 0.83 | RARB (0.67) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL9047784 | 0.83 | RARB (0.67) | RARARARBRARGRXRAPDK2 | |
| SCHEMBL8656647 | 0.83 | RARB (0.67) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL8690917 | 0.80 | MEN1 (0.55) | RARARARBRARGKMT2AKDM4E | |
| SCHEMBL8690840 | 0.78 | RARB (0.51) | RARARARBRARGKMT2AKDM4E | |
| SCHEMBL10959462 | 0.78 | RARA (0.68) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL8659260 | 0.77 | RARA (0.54) | RARARARBRARGKMT2ANPC1 | |
| SCHEMBL8692871 | 0.76 | MEN1 (0.40) | RARARARBRARGKMT2AKDM4E | |
| SCHEMBL8692906 | 0.75 | RARB (0.41) | RARARARBRARGKMT2AKDM4E | |
| SCHEMBL9051570 | 0.74 | RARB (0.56) | RARARARBRARGRXRAPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658553-B1 | Polycyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | CIRD GALDERMA (FR) | 1998-11-04 | — | — | EP | claimed |
| US-5723499-A | Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | C.I.R.D. GALDERMA (FR) | 1998-03-03 | — | — | US | claimed |
| US-5723499-A | Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | C.I.R.D. GALDERMA (FR) | 1998-03-03 | — | — | US | disclosed |