SCHEMBL8656752

SCHEMBL8656752

CO[CH]CCC=Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.47
IDO1 P14902 2/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
HTR2A P28223 3/20 0.44
TRPA1 O75762 1/20 0.44
PAM P19021 1/20 0.42
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
RAB9A P51151 1/20 0.41
RECQL P46063 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10430031 0.82 IDO1 (0.56) SIGMAR1IDO1HTR2ATRPA1PAM
SCHEMBL7939387 0.82 IDO1 (0.56) SIGMAR1IDO1HTR2ATRPA1PAM
SCHEMBL7568412 0.82 IDO1 (0.56) SIGMAR1IDO1HTR2ATRPA1PAM
SCHEMBL11134002 0.81 RELA (0.46) SIGMAR1IDO1MEN1KMT2AHTR2A
SCHEMBL15907605 0.78 MEN1 (0.61) SIGMAR1IDO1MEN1KMT2AHTR2A
SCHEMBL11259781 0.76 SIGMAR1 (0.44) SIGMAR1IDO1MEN1KMT2AHTR2A
SCHEMBL108128 0.74 SIGMAR1 (0.53) SIGMAR1IDO1MEN1KMT2AHTR2A
SCHEMBL78219 0.74 SIGMAR1 (0.53) SIGMAR1IDO1MEN1KMT2AHTR2A
Benzene SCHEMBL1226219 0.74 SIGMAR1 (0.53) SIGMAR1IDO1MEN1KMT2AHTR2A
Benzene SCHEMBL1226215 0.74 SIGMAR1 (0.53) SIGMAR1IDO1MEN1KMT2AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5833878-A DISPLAY COMPRISING POLYNORBORNANE RESIN FILMS; SHARPNESS JSR CORPORATION (JP) 1998-11-10 US disclosed
US-5516456-A Liquid crystal display panel JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-05-14 US disclosed
EP-0039871-B1 TWO-DIMENSIONAL DISPLAY DEVICE WITH AN ELECTRICALLY CONTROLLED FLUID LAYER, AND METHOD OF MAKING THE SAME SINTRA-ALCATEL Société Anonyme dite: (FR) 1984-01-04 EP disclosed
US-4422731-A Display unit with half-stud, spacer, connection layer and method of manufacturing Societe Anonyme dite, Societe Industrielle des Nouvelles Techniques Radioelectriques (FR) 1983-12-27 US disclosed