Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658136 | 0.86 | ALDH1A1 (0.30) | LMNAKMT2AALDH1A1 | |
| SCHEMBL8654394 | 0.86 | AR (0.38) | LMNAKMT2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8656854 | 0.84 | AR (0.37) | LMNAKMT2AALDH1A1HPGD | |
| SCHEMBL8656716 | 0.78 | AR (0.34) | LMNAALDH1A1HPGD | |
| SCHEMBL8658583 | 0.78 | KMT2A (0.36) | LMNAKMT2AALDH1A1HPGD | |
| SCHEMBL8658153 | 0.74 | AR (0.36) | LMNAKMT2AALDH1A1HPGD | |
| SCHEMBL8656613 | 0.73 | AR (0.36) | LMNAKMT2AALDH1A1HPGD | |
| SCHEMBL8656782 | 0.72 | — | — | |
| SCHEMBL8656860 | 0.71 | AR (0.36) | LMNAKMT2AALDH1A1HPGD | |
| SCHEMBL8655776 | 0.71 | LMNA (0.34) | LMNAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733922-A | Imidazole derivative, pharmaceutically acceptable salt thereof, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0728747-A1 | Imidazole derivative, pharmaceutically acceptable salt thereof, process of manufacture therefor, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1996-08-28 | — | — | EP | disclosed |