Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656211 | 0.85 | HPGD (0.39) | KMT2ALMNAHPGDPOLBMAPT | |
| SCHEMBL8657123 | 0.78 | LMNA (0.30) | KMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL8658136 | 0.74 | ALDH1A1 (0.30) | KMT2ALMNAALDH1A1 | |
| SCHEMBL3377470 | 0.71 | RAB9A (0.57) | KMT2ALMNAHPGDPOLBMAPT | |
| SCHEMBL9693793 | 0.70 | TP53 (0.60) | KMT2ALMNAHPGDPOLBMAPT | |
| SCHEMBL27512892 | 0.68 | KCNH2 (0.34) | HPGDALDH1A1 | |
| SCHEMBL8656782 | 0.68 | — | — | |
| SCHEMBL8653906 | 0.66 | CYP1A2 (0.47) | LMNAMAPTTSHRMAPK1L3MBTL1 | |
| SCHEMBL8176074 | 0.66 | AOC3 (0.37) | TSHRALDH1A1 | |
| SCHEMBL8656716 | 0.65 | AR (0.34) | LMNAHPGDPOLBMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733922-A | Imidazole derivative, pharmaceutically acceptable salt thereof, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0728747-A1 | Imidazole derivative, pharmaceutically acceptable salt thereof, process of manufacture therefor, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1996-08-28 | — | — | EP | disclosed |