Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775852 | 0.82 | KMT2A (0.58) | ALDH1A1KMT2AL3MBTL1KDM4EPIM1 | |
| SCHEMBL9085554 | 0.79 | KDM4E (0.49) | DPP4ALDH1A1KMT2AKDM4EHTT | |
| SCHEMBL11688348 | 0.78 | KMT2A (0.66) | ALDH1A1KMT2AKDM4EHPGDNPC1 | |
| SCHEMBL9194139 | 0.76 | KDM4E (0.46) | ALDH1A1KMT2AKDM4EPIM1HPGD | |
| SCHEMBL31276870 | 0.75 | KDM4E (0.70) | DPP4ALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL8942357 | 0.74 | KMT2A (0.66) | ALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL9083774 | 0.74 | KMT2A (0.39) | DPP4ALDH1A1KMT2AL3MBTL1HPGD | |
| SCHEMBL9083782 | 0.73 | KMT2A (0.38) | ALDH1A1KMT2AL3MBTL1KDM4EPIM1 | |
| SCHEMBL1033239 | 0.73 | KDM4E (0.46) | DPP4ALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL9192787 | 0.72 | ACHE (0.46) | ALDH1A1KDM4ELMNAPIM1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719764-B1 | 3-Phenylisoquinolin-1(2H)-one derivatives as ligands of benzodiazepine receptors associated with GABAA receptors | SYNTHELABO (FR) | 1998-11-04 | — | — | EP | disclosed |
| EP-0719764-A1 | 3-Phenylisoquinolin-1 (2H)-one derivatives as GABA receptor ligands | SYNTHELABO (FR) | 1996-07-03 | — | — | EP | disclosed |