Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | GALK1 | P51570 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18156389 | 0.84 | APP (0.44) | KMT2AHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL16578792 | 0.84 | L3MBTL1 (0.52) | KMT2AHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL8657181 | 0.82 | DPP4 (0.51) | KMT2AHPGDALDH1A1HSD17B10CASP1 | |
| SCHEMBL9085554 | 0.80 | KDM4E (0.49) | KMT2AHPGDALDH1A1GAAPKM | |
| SCHEMBL1035417 | 0.79 | PGR (0.56) | NPC1RAB9A | |
| SCHEMBL6824613 | 0.79 | KMT2A (0.51) | KMT2AHPGDALDH1A1PKMPDE4A | |
| SCHEMBL30160665 | 0.77 | MAPK1 (0.53) | KMT2AHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL28513461 | 0.77 | MAPK1 (0.53) | KMT2AHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL9194139 | 0.77 | KDM4E (0.46) | KMT2AHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL13180854 | 0.76 | HSD17B10 (0.53) | KMT2AHPGDALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11286240-B2 | Catalyst bound alpha radical and synthesis of OXO compounds using the same | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2022-03-29 | — | — | US | claimed |
| US-20210147364-A1 | A CATALYST BOUND ALPHA RADICAL AND SYNTHESIS OF OXO COMPOUNDS USING THE SAME | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2021-05-20 | — | — | US | claimed |
| US-11286240-B2 | Catalyst bound alpha radical and synthesis of OXO compounds using the same | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2022-03-29 | — | — | US | disclosed |
| US-20210147364-A1 | A CATALYST BOUND ALPHA RADICAL AND SYNTHESIS OF OXO COMPOUNDS USING THE SAME | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2021-05-20 | — | — | US | disclosed |
| US-9758459-B2 | Allosteric modulators of factor XIa as anticoagulant agents | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2017-09-12 | — | — | US | disclosed |
| US-9758459-B2 | Allosteric modulators of factor XIa as anticoagulant agents | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2017-09-12 | — | — | US | disclosed |
| US-20160311842-A1 | ALLOSTERIC MODULATORS OF FACTOR XIa AS ANTICOAGULANT AGENTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2016-10-27 | — | — | US | disclosed |
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11286240-B2 | Catalyst bound alpha radical and synthesis of OXO compounds using the same | CBR1, POR, CAT | KMT2A 2616/4885HPGD 230/4885ALDH1A1 256/4885 |
| US-20210147364-A1 | A CATALYST BOUND ALPHA RADICAL AND SYNTHESIS OF OXO COMPOUNDS USING THE SAME | CBR1, POR, CAT | KMT2A 2513/4885HPGD 244/4885ALDH1A1 230/4885 |
| US-20160311842-A1 | ALLOSTERIC MODULATORS OF FACTOR XIa AS ANTICOAGULANT AGENTS | TFPI, TFPI2, F10 | KMT2A 3856/4885HPGD 2554/4885ALDH1A1 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.