Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656787 | 0.91 | PTGS2 (0.39) | CA9CA12CA2PTGS1PTGS2 | |
| SCHEMBL8661261 | 0.90 | PTGS1 (0.40) | CA9CA12CA1CA2PTGS1 | |
| SCHEMBL8660155 | 0.90 | PTGS2 (0.40) | PTGS1PTGS2F10MAPT | |
| SCHEMBL8660177 | 0.88 | PTGS2 (0.47) | BRD4PTGS1PTGS2F10MAPT | |
| SCHEMBL8661288 | 0.88 | PTGS2 (0.39) | CA9CA12CA2PTGS1PTGS2 | |
| SCHEMBL8660146 | 0.87 | PTGS2 (0.47) | CA9CA12CA2PTGS1PTGS2 | |
| SCHEMBL8657315 | 0.87 | PTGS2 (0.43) | CA9CA12CA2PTGS1PTGS2 | |
| SCHEMBL8661927 | 0.87 | PTGS2 (0.36) | CA9CA12CA1CA2PTGS1 | |
| SCHEMBL8662796 | 0.86 | POLB (0.41) | CA9CA12CA2BRD4PTGS1 | |
| SCHEMBL8661454 | 0.86 | ABL1 (0.41) | CA9CA12CA2PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |