Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT1 | P34896 | 3/20 | 0.45 |
| ▸ | SHMT2 | P34897 | 3/20 | 0.45 |
| ▸ | FABP4 | P15090 | 4/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654878 | 1.00 | SHMT1 (0.45) | SHMT1SHMT2FABP4FABP5KMT2A | |
| SCHEMBL8663529 | 1.00 | SHMT1 (0.45) | SHMT1SHMT2FABP4FABP5KMT2A | |
| SCHEMBL8650591 | 0.99 | SHMT1 (0.46) | SHMT1SHMT2FABP4FABP5KMT2A | |
| SCHEMBL8654386 | 0.88 | ALPL (0.38) | KMT2AHSD11B1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL8652686 | 0.88 | ALPL (0.38) | KMT2AHSD11B1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL8651992 | 0.88 | ALPL (0.38) | KMT2AHSD11B1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL8657000 | 0.87 | SHMT1 (0.40) | SHMT1SHMT2TRPV1THRBLPAR1 | |
| SCHEMBL8654660 | 0.86 | P2RX7 (0.38) | SHMT1SHMT2KMT2AHSD11B1CYP2C9 | |
| SCHEMBL8652082 | 0.85 | SHMT1 (0.38) | SHMT1SHMT2FABP4FABP5KMT2A | |
| SCHEMBL8652492 | 0.85 | FFAR4 (0.40) | SHMT1SHMT2FABP4FABP5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |