Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 2/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10710192 | 0.79 | CYP2D6 (0.53) | LMNAHSD11B1 | |
| SCHEMBL8658684 | 0.78 | OGA (0.38) | OGAHSD11B1 | |
| SCHEMBL8661303 | 0.78 | OGA (0.38) | OGAHSD11B1 | |
| SCHEMBL14414892 | 0.73 | L3MBTL1 (0.44) | LMNAL3MBTL1 | |
| SCHEMBL8659393 | 0.68 | CHRM2 (0.31) | OGAL3MBTL1 | |
| SCHEMBL8657949 | 0.67 | LMNA (0.44) | LMNAHSD11B1 | |
| SCHEMBL15105088 | 0.61 | CYP2D6 (0.49) | — | |
| SCHEMBL8863358 | 0.61 | CYP11B1 (0.46) | OGA | |
| SCHEMBL1476498 | 0.60 | — | — | |
| SCHEMBL8661095 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756508-A | Muscarine antagonists | MERCK & CO., INC. (US) | 1998-05-26 | — | — | US | disclosed |