Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 6/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658684 | 1.00 | OGA (0.38) | OGACYP2D6MC4RTRPC5CHRM2 | |
| SCHEMBL8863358 | 0.80 | CYP11B1 (0.46) | OGACYP2D6MC4RCYP19A1 | |
| SCHEMBL8657944 | 0.78 | LMNA (0.34) | OGAHSD11B1 | |
| SCHEMBL8659393 | 0.74 | CHRM2 (0.31) | OGACHRM2 | |
| SCHEMBL19613500 | 0.74 | CYP2D6 (0.70) | CYP2D6MC4RTRPC5CHRM2CHRM1 | |
| SCHEMBL8099850 | 0.74 | CYP2D6 (0.70) | CYP2D6MC4RTRPC5CHRM2CHRM1 | |
| SCHEMBL1586528 | 0.74 | CYP2D6 (0.70) | CYP2D6MC4RTRPC5CHRM2CHRM1 | |
| SCHEMBL4601165 | 0.74 | CYP2D6 (0.70) | CYP2D6MC4RTRPC5CHRM2CHRM1 | |
| SCHEMBL13283877 | 0.74 | HSD11B1 (0.52) | CYP2D6MC4RCHRM2CHRM1HSD11B1 | |
| SCHEMBL12685149 | 0.73 | HSD11B1 (0.54) | CYP2D6MC4RCHRM2CHRM1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756508-A | Muscarine antagonists | MERCK & CO., INC. (US) | 1998-05-26 | — | — | US | disclosed |
| WO-1997016192-A1 | MUSCARINE ANTAGONISTS | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | disclosed |