Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 17/20 | 0.65 |
| ▸ | RARG | P13631 | 17/20 | 0.65 |
| ▸ | RARA | P10276 | 16/20 | 0.65 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.45 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690609 | 0.86 | RARA (0.54) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8657950 | 0.82 | RARG (0.59) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL3453631 | 0.79 | RARB (1.00) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL31266609 | 0.79 | RARB (1.00) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL2914641 | 0.76 | RARB (0.68) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8656889 | 0.75 | RARG (0.67) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL9374463 | 0.74 | RARA (0.90) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8658266 | 0.74 | RARB (0.65) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL6372194 | 0.73 | RARB (0.64) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL6379832 | 0.73 | RARG (0.64) | RARBRARGRARACYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658553-B1 | Polycyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | CIRD GALDERMA (FR) | 1998-11-04 | — | — | EP | claimed |
| US-5723499-A | Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | C.I.R.D. GALDERMA (FR) | 1998-03-03 | — | — | US | claimed |
| EP-0658553-B1 | Polycyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses thereof | CIRD GALDERMA (FR) | 1998-11-04 | — | — | EP | disclosed |
| US-5723499-A | Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | C.I.R.D. GALDERMA (FR) | 1998-03-03 | — | — | US | disclosed |
| EP-0658553-A1 | Polycyclic aromatic compounds, pharmaceutical compositions containing them and uses thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1995-06-21 | — | — | EP | disclosed |