Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 9/20 | 0.54 |
| ▸ | RARB | P10826 | 9/20 | 0.54 |
| ▸ | RARG | P13631 | 8/20 | 0.54 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657948 | 0.86 | RARB (0.65) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL8657950 | 0.79 | RARG (0.59) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL8660116 | 0.78 | RARB (0.56) | RARARARBRARGCYP3A4CYP11B1 | |
| SCHEMBL8688231 | 0.77 | RARG (0.55) | RARARARBRARGCYP3A4CYP11B1 | |
| SCHEMBL8690673 | 0.77 | RARG (0.55) | RARARARBRARGCYP3A4CYP11B1 | |
| SCHEMBL8661405 | 0.76 | RARB (0.54) | RARARARBRARGCYP3A4CYP11B1 | |
| SCHEMBL12766140 | 0.75 | CYP11B1 (0.50) | ALPLCYP3A4CYP11B1CYP11B2 | |
| SCHEMBL8691493 | 0.75 | RARA (0.53) | RARARARBRARGCYP3A4CYP11B1 | |
| SCHEMBL18775432 | 0.74 | RARB (0.73) | RARARARBRARGCYP3A4CYP11B1 | |
| SCHEMBL17327788 | 0.73 | RARA (0.67) | RARARARBRARGCYP3A4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723499-A | Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | C.I.R.D. GALDERMA (FR) | 1998-03-03 | — | — | US | disclosed |