SCHEMBL2914641

SCHEMBL2914641

CC1(C)CCC(C)(C)c2cc3cc(-c4ccc(C(=O)O)c(O)c4)ccc3cc21

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RARB P10826 11/20 0.68
RARG P13631 9/20 0.68
RARA P10276 9/20 0.68
RXRA P19793 2/20 0.50
ACMSD Q8TDX5 2/20 0.50
HNF4A P41235 1/20 0.50
CYP26A1 O43174 1/20 0.47
CYP26B1 Q9NR63 1/20 0.47
XDH P47989 3/20 0.46
MEN1 O00255 1/20 0.43
THRB P10828 1/20 0.43
RECQL P46063 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8660116 0.85 RARB (0.56) RARBRARGRARARXRACYP26A1
SCHEMBL8656889 0.85 RARG (0.67) RARBRARGRARARXRACYP26A1
SCHEMBL6379832 0.83 RARG (0.64) RARBRARGRARARXRACYP26A1
SCHEMBL31266609 0.81 RARB (1.00) RARBRARGRARARXRACYP26A1
SCHEMBL3453631 0.81 RARB (1.00) RARBRARGRARARXRACYP26A1
SCHEMBL7902107 0.80 RARG (0.63) RARBRARGRARARXRACYP26A1
SCHEMBL8656079 0.79 RARG (0.58) RARBRARGRARARXRAHNF4A
SCHEMBL14425251 0.77 RARB (0.63) RARBRARGRARARXRACYP26A1
SCHEMBL5846597 0.76 RARG (0.62) RARBRARGRARARXRAACMSD
SCHEMBL8442921 0.76 RARG (0.55) RARBRARGRARARXRAHNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1255543-B1 USE OF RETINOID-TYPE COMPOUNDS AS ANTIBACTERIAL AGENTS AGAINST STAPHYLOCOCCUS AUREUS GALDERMA RES & DEV (FR) 2010-09-01 EP claimed
US-6858647-B2 Retinoid compounds suited for antibacterial applications GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2005-02-22 US claimed
US-20030055110-A1 Retinoid compounds suited for antibacterial applications GALDERMA RESEARCH & DEVELOPMENT (FR) 2003-03-20 US claimed
EP-0658553-B1 Polycyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses thereof CIRD GALDERMA (FR) 1998-11-04 EP claimed
US-5723499-A Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof C.I.R.D. GALDERMA (FR) 1998-03-03 US claimed
EP-0658553-A1 Polycyclic aromatic compounds, pharmaceutical compositions containing them and uses thereof CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) 1995-06-21 EP claimed
US-20260035353-A1 PHENOL DERIVATIVES FOR USE AS ANTIMICROBIAL, ANTIBACTERIAL, BACTERICIDE SPECIAL PRODUCTS LINE S P A (IT) 2026-02-05 US disclosed
US-20220281835-A1 PHENOL DERIVATIVES FOR USE AS ANTIMICROBIAL, ANTIBACTERIAL, BACTERICIDE SPECIAL PRODUCTS LINE S P A (IT) 2022-09-08 US disclosed
EP-3962887-A1 PHENOL DERIVATIVES FOR USE AS ANTIMICROBIAL, ANTIBACTERIAL, BACTERICIDE Special Product's Line S.p.A. (IT) 2022-03-09 EP disclosed
US-6858647-B2 Retinoid compounds suited for antibacterial applications GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2005-02-22 US disclosed
EP-0658553-B1 Polycyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and uses thereof CIRD GALDERMA (FR) 1998-11-04 EP disclosed
US-5723499-A Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof C.I.R.D. GALDERMA (FR) 1998-03-03 US disclosed
EP-0658553-A1 Polycyclic aromatic compounds, pharmaceutical compositions containing them and uses thereof CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) 1995-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035353-A1 PHENOL DERIVATIVES FOR USE AS ANTIMICROBIAL, ANTIBACTERIAL, BACTERICIDE TLR7, GANC, ARG1 RARB 2413/4885RARG 2152/4885RARA 2620/4885
US-20220281835-A1 PHENOL DERIVATIVES FOR USE AS ANTIMICROBIAL, ANTIBACTERIAL, BACTERICIDE UROD, PPARD, PGLS RARB 1666/4885RARG 2311/4885RARA 1672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.