Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NAT1 | P18440 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 3/20 | 0.51 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660027 | 0.88 | NAT1 (0.64) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8661065 | 0.86 | MCOLN3 (0.56) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8661273 | 0.86 | MCOLN3 (0.63) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8660236 | 0.85 | STAT3 (0.56) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8660227 | 0.84 | MCOLN3 (0.61) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8661254 | 0.84 | MCOLN3 (0.61) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8662887 | 0.84 | MCOLN3 (0.54) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL5410713 | 0.83 | MCOLN3 (0.78) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8662804 | 0.83 | PTGES2 (0.61) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8659492 | 0.82 | ACLY (0.53) | ERBB2HSP90AA1HSP90AB1ACLYSLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |