Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 2/20 | 0.49 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661065 | 0.88 | MCOLN3 (0.56) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8660236 | 0.87 | STAT3 (0.56) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8661296 | 0.86 | SLC40A1 (0.48) | MEN1KMT2ATSHRALDH1A1KAT6A | |
| SCHEMBL8663418 | 0.86 | STAT3 (0.59) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8661254 | 0.86 | MCOLN3 (0.61) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8659219 | 0.85 | STAT3 (0.57) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8662804 | 0.85 | PTGES2 (0.61) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8657978 | 0.85 | LMNA (0.50) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8661642 | 0.84 | MCOLN3 (0.57) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8658016 | 0.84 | MCOLN3 (0.57) | MCOLN3LMNACA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |