Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PTGES2 | Q9H7Z7 | 5/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661254 | 0.88 | MCOLN3 (0.61) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8662887 | 0.88 | MCOLN3 (0.54) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8662804 | 0.88 | PTGES2 (0.61) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8660236 | 0.87 | STAT3 (0.56) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8658016 | 0.86 | MCOLN3 (0.57) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8660227 | 0.85 | MCOLN3 (0.61) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8656731 | 0.85 | MCOLN3 (0.53) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8657978 | 0.85 | LMNA (0.50) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8657888 | 0.83 | ALDH1A1 (0.61) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8659295 | 0.83 | SLC40A1 (0.51) | ALDH1A1GAAALOX15HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |