Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661588 | 0.93 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1LMNAL3MBTL1TP53 | |
| SCHEMBL8656393 | 0.93 | HTR7 (0.35) | SMN1; SMN2TSHRTP53BRD4 | |
| SCHEMBL8654546 | 0.90 | SMN1; SMN2 (0.32) | SMN1; SMN2ALDH1A1LMNAL3MBTL1KDM4E | |
| SCHEMBL8656677 | 0.90 | CHRM1 (0.33) | PAOXSMN1; SMN2TSHRALDH1A1LMNA | |
| SCHEMBL8658456 | 0.89 | GAA (0.34) | SMN1; SMN2ALDH1A1LMNAGLAFPR3 | |
| SCHEMBL8655552 | 0.89 | SMN1; SMN2 (0.34) | SMN1; SMN2GLA | |
| SCHEMBL8655661 | 0.89 | SMN1; SMN2 (0.38) | PAOXSMN1; SMN2TSHRALDH1A1LMNA | |
| SCHEMBL8659458 | 0.88 | FPR3 (0.32) | PAOXSMN1; SMN2GLAFPR3FPR2 | |
| SCHEMBL8657068 | 0.86 | MAOB (0.33) | SMN1; SMN2FPR3FPR2TP53 | |
| SCHEMBL8656723 | 0.85 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1LMNAFPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |