Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656293 | 0.92 | OPRL1 (0.35) | OPRL1GRM2 | |
| SCHEMBL8658456 | 0.91 | GAA (0.34) | FPR3FPR2SMN1; SMN2GLAKAT2B | |
| SCHEMBL8655360 | 0.89 | SMN1; SMN2 (0.34) | FPR3FPR2SMN1; SMN2GLA | |
| SCHEMBL8658494 | 0.88 | PAOX (0.35) | FPR3FPR2SMN1; SMN2GLAPAOX | |
| SCHEMBL8654666 | 0.88 | HTR7 (0.39) | CHRM2SIGMAR1 | |
| SCHEMBL8656723 | 0.86 | SMN1; SMN2 (0.38) | FPR3FPR2SMN1; SMN2 | |
| SCHEMBL8655456 | 0.86 | SMN1; SMN2 (0.34) | SMN1; SMN2HRH2HRH1GLA | |
| SCHEMBL8658344 | 0.86 | GLA (0.33) | SMN1; SMN2HRH2HRH1GLA | |
| SCHEMBL8657068 | 0.86 | MAOB (0.33) | FPR3FPR2SMN1; SMN2HTR4 | |
| SCHEMBL8657783 | 0.86 | CACNA1G (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |