Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660424 | 0.91 | LMNA (0.34) | GAAKMT2ALMNAMAPTNPSR1 | |
| SCHEMBL8658101 | 0.87 | LMNA (0.34) | LMNAMAPT | |
| SCHEMBL8658385 | 0.86 | — | — | |
| SCHEMBL8655776 | 0.83 | LMNA (0.34) | KMT2ALMNAMAPTNPSR1HPGD | |
| SCHEMBL8653399 | 0.82 | ALDH1A1 (0.38) | KMT2ALMNAMAPTHPGDKDM4E | |
| SCHEMBL8658215 | 0.79 | NPC1 (0.30) | SMN1; SMN2 | |
| SCHEMBL8654571 | 0.75 | ALOX5 (0.36) | KMT2ALMNAMAPTNPSR1HPGD | |
| SCHEMBL8670813 | 0.74 | GAA (0.31) | GAAKMT2A | |
| SCHEMBL8655371 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL8653534 | 0.72 | ALDH1A1 (0.34) | HPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733922-A | Imidazole derivative, pharmaceutically acceptable salt thereof, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0728747-A1 | Imidazole derivative, pharmaceutically acceptable salt thereof, process of manufacture therefor, and anti-ulcer drug including such derivative or salt | ARAX CO., LTD. (JP) | 1996-08-28 | — | — | EP | disclosed |