SCHEMBL8658707

SCHEMBL8658707

CC(c1ccc(OCCO)cc1)(c1ccc(OCCO)cc1)c1ccc2ccccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.53
CYP3A4 P08684 1/20 0.53
ALDH1A1 P00352 2/20 0.49
RECQL P46063 1/20 0.49
KDM4E B2RXH2 3/20 0.47
MAPK1 P28482 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NR1H2 P55055 1/20 0.45
PPARA Q07869 3/20 0.45
GAA P10253 1/20 0.43
CHRNB2 P17787 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA7 P36544 1/20 0.43
CHRNA4 P43681 1/20 0.43
PPARG P37231 2/20 0.42
PPARD Q03181 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL347297 0.85 ALDH1A1 (0.62) SMN1; SMN2CYP3A4ALDH1A1RECQLKDM4E
SCHEMBL4254052 0.85 SMN1; SMN2 (0.68) SMN1; SMN2CYP3A4ALDH1A1RECQLKDM4E
SCHEMBL23082206 0.83 ALDH1A1 (0.58) SMN1; SMN2CYP3A4ALDH1A1RECQLKDM4E
SCHEMBL29385642 0.82 KDM4E (0.68) SMN1; SMN2ALDH1A1RECQLKDM4EMAPK1
SCHEMBL432069 0.82 KDM4E (0.68) SMN1; SMN2ALDH1A1RECQLKDM4EMAPK1
SCHEMBL7635627 0.77 CHRNB2 (0.60) SMN1; SMN2ALDH1A1RECQLKDM4EMAPK1
SCHEMBL9043875 0.77 KDM4E (0.60) SMN1; SMN2ALDH1A1RECQLKDM4EMAPK1
SCHEMBL10839869 0.76 ESR1 (0.55) CYP3A4ALDH1A1TDP1
SCHEMBL607523 0.76 SMN1; SMN2 (0.68) SMN1; SMN2CYP3A4ALDH1A1RECQLKDM4E
SCHEMBL19912050 0.76 CYP3A4 (0.56) SMN1; SMN2CYP3A4ALDH1A1RECQLKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723264-A RADIATION TRANSPARENT POLYESTER MULTILAYER ELEMENT ON SUBSTRATE EASTMAN KODAK COMPANY (US) 1998-03-03 US disclosed
EP-0756205-A2 Pattern transfer techniques for fabrication of lenslet arrays using specialized polyesters EASTMAN KODAK COMPANY (US) 1997-01-29 EP disclosed