SCHEMBL432069

SCHEMBL432069

OCCOc1ccc2ccccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.68
TDP1 Q9NUW8 2/20 0.68
MAPK1 P28482 1/20 0.68
ALDH1A1 P00352 2/20 0.59
RECQL P46063 1/20 0.59
AGXT P21549 2/20 0.59
NPC1 O15118 4/20 0.58
RAB9A P51151 4/20 0.58
MAPT P10636 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
PTPN7 P35236 1/20 0.56
ALOX5 P09917 1/20 0.55
PPARG P37231 3/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA9 Q16790 1/20 0.53
HDAC1 Q13547 1/20 0.53
HTT P42858 2/20 0.51
PPARD Q03181 1/20 0.51
PPARA Q07869 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29385642 1.00 KDM4E (0.68) KDM4ETDP1MAPK1ALDH1A1RECQL
SCHEMBL9043875 0.94 KDM4E (0.60) KDM4ETDP1MAPK1ALDH1A1RECQL
SCHEMBL8361854 0.91 CA1 (0.56) KDM4ETDP1MAPK1ALDH1A1RECQL
SCHEMBL30498736 0.91 CA1 (0.56) KDM4ETDP1MAPK1ALDH1A1RECQL
SCHEMBL8615953 0.91 CA1 (0.59) KDM4ETDP1MAPK1ALDH1A1RECQL
SCHEMBL470915 0.90 TDP1 (0.66) KDM4ETDP1MAPK1ALDH1A1AGXT
SCHEMBL13174723 0.89 KDM4E (0.82) KDM4ETDP1MAPK1ALDH1A1RECQL
SCHEMBL16021984 0.89 KDM4E (0.82) KDM4ETDP1MAPK1ALDH1A1RECQL
SCHEMBL16021974 0.89 KDM4E (0.82) KDM4ETDP1MAPK1ALDH1A1RECQL
SCHEMBL16021964 0.89 KDM4E (0.82) KDM4ETDP1MAPK1ALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 500 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114394887-A Phenyloxyethanol compound and preparation method thereof 江苏锐鸣材料科技有限公司 2022-04-26 CN claimed
WO-2021054927-A2 GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS SOUTH DAKOTA BOARD OF REGENTS (US) 2021-03-25 WO claimed
US-20200048305-A1 GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS SOUTH DAKOTA BOARD OF REGENTS (US) 2020-02-13 US claimed
EP-1889896-B1 LUBRICATING OIL COMPOSITION CONTAINING DETERGENT ADDITIVES INFINEUM INT LTD (GB) 2019-05-29 EP claimed
EP-1693434-B1 SOOT DISPERSANTS AND LUBRICATING OIL COMPOSITIONS CONTAINING SAME INFINEUM INT LTD (GB) 2019-03-20 EP claimed
EP-1959003-B1 Soot dispersants and lubricating oil compositions containing same INFINEUM INT LTD (GB) 2019-01-02 EP claimed
US-9622969-B2 Polymer conjugated protein micelles SOUTH DAKOTA STATE UNIV (US) 2017-04-18 US claimed
CN-103274937-B Soot dispersion agent and the lubricating oil composition containing this dispersion agent ENFENORM INTERNATIONAL CO. (GB) 2016-02-03 CN claimed
US-20140370110-A1 POLYMER CONJUGATED PROTEIN MICELLES SOUTH DAKOTA STATE UNIVERSITY (US) 2014-12-18 US claimed
CN-101240073-B Soot dispersants and lubricating oil compositions containing same INFINEUM INT LTD 2013-11-27 CN claimed
US-20080039349-A1 Lubricating oil composition INFINEUM INTERNATIONAL LIMITED (GB) 2008-02-14 US claimed
US-20080028672-A1 Diesel fuel compositions CAPROTTI RINALDO 2008-02-07 US claimed
EP-1884556-A2 Improvements in Diesel fuel compositions Infineum International Limited (GB) 2008-02-06 EP claimed
CN-101117599-A Improvements in diesel fuel compositions INFINEUM INT LTD (GB) 2008-02-06 CN claimed
CN-1830935-A Soot dispersants and lubricating oil compositions containing the same INFINEUM INT LTD (GB) 2006-09-13 CN claimed
US-20060189492-A1 Soot dispersants and lubricating oil compositions containing same INFINEUM INTERNATIONAL LIMITED (GB) 2006-08-24 US claimed
EP-1693434-A2 Soot dispersants and lubricating oil compositions containing same Infineum International Limited (GB) 2006-08-23 EP claimed
EP-1002021-B1 DISPERSING AGENTS AND DISPERSIONS MADE THEREFROM ICI AMERICA INC (US) 2001-08-29 EP claimed
EP-1002021-A1 DISPERSING AGENTS AND DISPERSIONS MADE THEREFROM ICI AMERICAS INC. (US) 2000-05-24 EP claimed
WO-1999005225-A1 DISPERSING AGENTS AND DISPERSIONS MADE THEREFROM ICI AMERICAS INC. (US) 1999-02-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048305-A1 GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS GSTK1, GSTO1, GSTM2 KDM4E 4520/4885TDP1 3971/4885MAPK1 4143/4885
US-20140370110-A1 POLYMER CONJUGATED PROTEIN MICELLES MTDH, PSMG3, GHITM KDM4E 3234/4885TDP1 3662/4885MAPK1 3828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.