SCHEMBL8658772

SCHEMBL8658772

CCCCCCNC(=O)n1ccnc1S

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ASAH1 Q13510 5/20 0.55
LMNA P02545 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPK3 P27361 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SQOR Q9Y6N5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6225068 0.85 ASAH1 (0.54) ASAH1LMNACYP3A4CYP2D6MAPK3
SCHEMBL8592380 0.83 ASAH1 (0.52) ASAH1LMNACYP3A4CYP2D6MAPK3
SCHEMBL160349 0.78 ASAH1 (0.46) ASAH1LMNACYP3A4CYP2D6MAPK3
SCHEMBL5150777 0.75 NAAA (0.59) SMN1; SMN2
SCHEMBL160287 0.71 BCHE (0.41) ASAH1LMNASMN1; SMN2
SCHEMBL8658768 0.70 TAS1R3 (0.38)
SCHEMBL10705766 0.70 NAAA (0.53) SMN1; SMN2
SCHEMBL29003729 0.70 BCHE (0.40) ASAH1LMNASMN1; SMN2
SCHEMBL29795663 0.69 ASAH1 (0.97) ASAH1
SCHEMBL11365469 0.69 TLR8 (0.38) ASAH1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0436027-B1 METHOD OF TREATING SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO LTD (JP) 1998-10-14 EP disclosed
US-5780198-A MULTILAYER; CONTAINS A HYDRAZINE NUCLEATING AGENT AND A REDOX COMPOUND CAPABLE OF RELEASING A DEVELOPMENT INHIBITOR WHEN THE REDOX COMPOUND IS OXIDIZED; ULTRAHIGH CONTRAST IMAGE WITH BROAD DOT GRADATION FUJI PHOTO FILM CO., LTD. (JP) 1998-07-14 US disclosed
EP-0442323-B1 Silver halide color reversal photographic material capable of providing interimage effect FUJI PHOTO FILM CO LTD (JP) 1997-10-15 EP disclosed
EP-0420005-B1 High contrast silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-07-10 EP disclosed
EP-0395069-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1996-07-10 EP disclosed
EP-0335319-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-06-05 EP disclosed
EP-0398285-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1995-09-13 EP disclosed
EP-0393720-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1995-08-23 EP disclosed
US-5395732-A Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1995-03-07 US disclosed
US-5278025-A Silver halide photographic materials for imagewise exposure and development FUJI PHOTO FILM CO., LTD. (JP) 1994-01-11 US disclosed
US-5075208-A Releasing a photographically useful compound upon reduction FUJI PHOTO FILM CO., LTD. (JP) 1991-12-24 US disclosed
EP-0442323-A2 Silver halide color reversal photographic material capable of providing interimage effect FUJI PHOTO FILM CO., LTD. (JP) 1991-08-21 EP disclosed
EP-0436027-A1 METHOD OF TREATING SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-07-10 EP disclosed
US-5006444-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-04-09 US disclosed
EP-0420005-A1 high contrast silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-04-03 EP disclosed
EP-0398285-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-11-22 EP disclosed
EP-0395069-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-10-31 EP disclosed
EP-0393720-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1990-10-24 EP disclosed
EP-0335319-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-10-04 EP disclosed
US-4737442-A INCLUDING A SENSITIZER AND A BLOCKED DEVELOPMENT RESTRAINER; FREE OF BLACK SPOTS FUJI PHOTO FILM CO., LTD. (JP) 1988-04-12 US disclosed