Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 9/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655652 | 0.95 | ACHE (0.43) | CHRM4ACHEBCHEALOX5MAOA | |
| SCHEMBL8659262 | 0.95 | ACHE (0.43) | CHRM4ACHEBCHEALOX5MAOA | |
| SCHEMBL8654508 | 0.92 | ACHE (0.44) | CHRM4ACHEBCHEALOX5MAOA | |
| SCHEMBL8655178 | 0.91 | ACHE (0.45) | CHRM4ACHEBCHE | |
| SCHEMBL8656276 | 0.91 | ALDH1A1 (0.41) | ACHE | |
| SCHEMBL8655966 | 0.91 | ACHE (0.42) | CHRM4ACHEBCHEALOX5MAOA | |
| SCHEMBL8658613 | 0.89 | ALDH1A1 (0.42) | — | |
| SCHEMBL8655866 | 0.88 | ALDH1A1 (0.41) | — | |
| SCHEMBL8659466 | 0.87 | ACHE (0.43) | CHRM4ACHEBCHEALOX5 | |
| SCHEMBL8655635 | 0.87 | ACHE (0.43) | CHRM4ACHEBCHEALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |