Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658613 | 0.94 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL8655866 | 0.94 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL8657670 | 0.92 | KMT2A (0.44) | ALDH1A1TSHRKMT2AMEN1MAPT | |
| SCHEMBL8659079 | 0.91 | CHRM4 (0.43) | ACHE | |
| SCHEMBL8655668 | 0.90 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL8655652 | 0.89 | ACHE (0.43) | FAAHACHE | |
| SCHEMBL8659262 | 0.89 | ACHE (0.43) | ACHE | |
| SCHEMBL8655083 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TSHRKMT2AMEN1MAPT | |
| SCHEMBL8657121 | 0.87 | CACNA1G (0.42) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL8661291 | 0.86 | KMT2A (0.45) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |