Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658434 | 0.95 | HTR7 (0.32) | CHRM1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL8659153 | 0.94 | HTR7 (0.37) | S1PR5CHRM1CHRM2CYP1A2MAPK1 | |
| SCHEMBL8659155 | 0.91 | CYP1A2 (0.37) | CHRM1CHRM2CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL8655420 | 0.90 | S1PR5 (0.37) | S1PR5CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL8656704 | 0.89 | GAA (0.33) | CHRM1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL8655832 | 0.89 | HTR7 (0.37) | CHRM1CHRM2GAAHTR7 | |
| SCHEMBL8656794 | 0.89 | S1PR5 (0.34) | S1PR5CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL8655755 | 0.89 | HTR7 (0.41) | CHRM1CHRM2CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL8657674 | 0.87 | CHRM1 (0.34) | S1PR5CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL8661418 | 0.86 | SMN1; SMN2 (0.37) | SMN1; SMN2GAAHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |