Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658396 | 0.96 | HTR7 (0.41) | HTR7GRIN1GRIN2BCHRM2CHRM1 | |
| SCHEMBL8659427 | 0.92 | HTR7 (0.41) | HTR7GRIN1GRIN2BCHRM2CHRM1 | |
| SCHEMBL8659153 | 0.91 | HTR7 (0.37) | HTR7GRIN1GRIN2BCHRM2CHRM1 | |
| SCHEMBL8659155 | 0.89 | CYP1A2 (0.37) | HTR7GRIN1GRIN2BCHRM2CHRM1 | |
| SCHEMBL8654666 | 0.89 | HTR7 (0.39) | HTR7GRIN1GRIN2BCHRM2CHRM1 | |
| SCHEMBL8659172 | 0.89 | S1PR5 (0.34) | HTR7CHRM2CHRM1CYP1A2MAPK1 | |
| SCHEMBL8655832 | 0.86 | HTR7 (0.37) | HTR7GRIN1GRIN2BCHRM2CHRM1 | |
| SCHEMBL8658006 | 0.85 | HTR7 (0.39) | HTR7GRIN1GRIN2BCHRM2CHRM1 | |
| SCHEMBL8655407 | 0.85 | HTR7 (0.40) | HTR7GRIN1GRIN2BCHRM2CHRM1 | |
| SCHEMBL8658466 | 0.84 | CYP1A2 (0.38) | HTR7CYP1A2MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |