Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655832 | 0.95 | HTR7 (0.37) | HTR7CHRM2CHRM1GAAGRIN1 | |
| SCHEMBL8659172 | 0.94 | S1PR5 (0.34) | HTR7S1PR5CHRM2CHRM1GAA | |
| SCHEMBL8655755 | 0.91 | HTR7 (0.41) | HTR7CHRM2CHRM1CYP1A2MAPK1 | |
| SCHEMBL8659270 | 0.90 | HTR7 (0.36) | HTR7CHRM2CHRM1GAAGRIN1 | |
| SCHEMBL8655420 | 0.90 | S1PR5 (0.37) | S1PR5CHRM2CHRM1CYP1A2MAPK1 | |
| SCHEMBL8654724 | 0.90 | GAA (0.35) | HTR7CHRM2CHRM1GAACYP1A2 | |
| SCHEMBL8658434 | 0.89 | HTR7 (0.32) | HTR7CHRM2CHRM1GAA | |
| SCHEMBL8655407 | 0.88 | HTR7 (0.40) | HTR7CHRM2CHRM1GRIN1GRIN2B | |
| SCHEMBL8658396 | 0.87 | HTR7 (0.41) | HTR7CHRM2CHRM1GRIN1GRIN2B | |
| SCHEMBL8659155 | 0.87 | CYP1A2 (0.37) | HTR7CHRM2CHRM1CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |