SCHEMBL8659359

SCHEMBL8659359

Cc1cn([C@H]2CC(O)[C@@H](CC(S)c3c4ccccc4cc4ccccc34)O2)c(=O)[nH]c1=O

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TK1 P04183 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8656828 0.86 TK1 (0.51) TK1
SCHEMBL8658422 0.83 TK1 (0.54) TK1
SCHEMBL9017699 0.80 TK1 (0.49) TK1
SCHEMBL8658418 0.80 TK1 (0.49) TK1
SCHEMBL17791952 0.78 TK1 (0.62) TK1
SCHEMBL8654924 0.76 TK1 (0.65) TK1
SCHEMBL778860 0.76 TK1 (0.65) TK1
SCHEMBL655193 0.76 TK1 (0.67) TK1
SCHEMBL8438318 0.75 POLB (0.67) TK1
SCHEMBL3272723 0.75 POLB (0.67) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5807837-A ADMINISTERING TO TREAT HIV INFECTIONS TO INHIBIT THE REPLICATION OF FOREIGN NUCLEIC ACIDS IN A NORMAL CELL SANKYO COMPANY, LIMITED (JP) 1998-09-15 US disclosed