SCHEMBL778860

SCHEMBL778860

Cc1cn([C@H]2C[C@H](O)[C@@H](CS)O2)c(=O)[nH]c1=O

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.65
POLB P06746 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8654924 1.00 TK1 (0.65) TK1POLB
Triphosphate SCHEMBL6046309 0.90 POLB (0.68) TK1POLB
SCHEMBL655193 0.90 TK1 (0.67) TK1POLB
Doxribtimine SCHEMBL767986 0.89 TK1 (0.73) TK1
SCHEMBL19224119 0.89 TK1 (0.69) TK1POLB
SCHEMBL14063727 0.89 TK1 (0.69) TK1POLB
SCHEMBL12352406 0.89 TK1 (0.69) TK1POLB
Doxribtimine SCHEMBL21078835 0.89 TK1 (0.73) TK1
Doxribtimine SCHEMBL2722555 0.89 TK1 (0.73) TK1
Doxribtimine SCHEMBL10382149 0.89 TK1 (0.73) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024011146-A1 A SYNTHETIC PROTEIN-LEVEL NEURAL NETWORK IN MAMMALIAN CELLS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2024-01-11 WO claimed
CN-109312313-A For treating the mRNA therapy of ornithine transcarbamylase deficiency disease 川斯勒佰尔公司 2019-02-05 CN claimed
CN-106413811-A MRNA therapy for deficiency of argininosuccinate synthetase 夏尔人类遗传性治疗公司 2017-02-15 CN claimed
US-8609677-B2 Molecules for the photodynamic treatment of tumors and hyperplasias Yagna Limited (GB) 2013-12-17 US claimed
US-20130226136-A1 Molecules for the Photodynamic Treatment of Tumors and Hyperplasias HUMANITARIAN SCIENTIFIC LLC 2013-08-29 US claimed
US-20260103707-A1 NOVEL COMPOUND AND APPLICATION THEREOF KYLONOVA XIAMEN BIOPHARMA CO LTD (CN) 2026-04-16 US disclosed
US-12516317-B1 Binding and catalytic molecules built from expanded DNA BENNER STEVEN A (US) 2026-01-06 US disclosed
WO-2025264548-A2 MODIFIED POLYNUCLEIC ACID MOLECULES TARGETING AGT AND USES THEREOF SIRIUS THERAPEUTICS, INC. (US) 2025-12-26 WO disclosed
EP-4665405-A1 DNA COMPOSITIONS COMPRISING MODIFIED URACIL Flagship Pioneering Innovations VII, LLC (US) 2025-12-24 EP disclosed
WO-2025235375-A1 COMPOSITIONS AND METHODS FOR CONTROLLING CELLULAR RESPONSES THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-11-13 WO disclosed
US-20250241848-A1 NANOPARTICLE COMPOSITIONS, FORMULATIONS THEREOF, AND USES THEREFOR ANTERIOS, INC. (US) 2025-07-31 US disclosed
WO-2025088373-A1 COMPOSITIONS AND METHODS OF MODULATING LONG NONCODING TRANSCRIPTS ASSOCIATED WITH ARDS INDUCED PULMONARY FIBROSIS HAYA THERAPEUTICS SA (CH) 2025-05-01 WO disclosed
US-5145840-A Treatment of virac and bacterial infections; aids BURROUGHS WELLCOME CO. (US) 1992-09-08 US disclosed
EP-0498843-A1 OLIGONUCLEOTIDE ANALOGS WITH NOVEL LINKAGES. GILEAD SCIENCES INC (US) 1992-08-19 EP disclosed
US-5064946-A 3-azido-2,3-dideoxy-B-D-erythro-pentofuranosyl derivatives of 4(1H)-pyrimidinones; antiretroviral, anti-AIDS BURROUGHS WELLCOME CO. (US) 1991-11-12 US disclosed
WO-1991006629-A1 OLIGONUCLEOTIDE ANALOGS WITH NOVEL LINKAGES GILEAD SCIENCES, INC. (US) 1991-05-16 WO disclosed
WO-1991004982-A1 FURTHER ANTIVIRAL PYRIMIDINE NUCLEOSIDES UNIVERSITY OF BIRMINGHAM (GB) 1991-04-18 WO disclosed
EP-0422090-A1 DERIVATIVES OF NUCLEOSIDES WHICH MAY BE USED FOR THE SYNTHESIS OF MARKED OLIGONUCLEOTIDES, AND OLIGONUCLEOTIDES OBTAINED FROM THESE DERIVATIVES AND THEIR SYNTHESIS. CIS BIO INT (FR) 1991-04-17 EP disclosed
WO-1989012642-A1 DERIVATIVES OF NUCLEOSIDES WHICH MAY BE USED FOR THE SYNTHESIS OF MARKED OLIGONUCLEOTIDES, AND OLIGONUCLEOTIDES OBTAINED FROM THESE DERIVATIVES AND THEIR SYNTHESIS CIS BIO INTERNATIONAL (FR) 1989-12-28 WO disclosed
EP-0217580-A2 Therapeutic nucleosides THE WELLCOME FOUNDATION LIMITED (GB) 1987-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250241848-A1 NANOPARTICLE COMPOSITIONS, FORMULATIONS THEREOF, AND USES THEREFOR TSG101, NPC1L1, NPC1 TK1 1670/4885POLB 3385/4885
US-20260103707-A1 NOVEL COMPOUND AND APPLICATION THEREOF GALNT10, FUT5, FUT6 TK1 1033/4885POLB 1725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.