Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 13/20 | 0.49 |
| ▸ | CA2 | P00918 | 13/20 | 0.49 |
| ▸ | CA9 | Q16790 | 13/20 | 0.49 |
| ▸ | CA12 | O43570 | 12/20 | 0.49 |
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.49 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.48 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660349 | 1.00 | PRKCA (0.52) | PRKCAAKT1PTK2TSHRCA1 | |
| SCHEMBL8977510 | 0.82 | TSHR (0.61) | PRKCAAKT1PTK2TSHRCA1 | |
| SCHEMBL13655528 | 0.79 | CYP2D6 (0.57) | PRKCAAKT1PTK2TSHRCA1 | |
| SCHEMBL14304869 | 0.79 | CYP2D6 (0.57) | PRKCAAKT1PTK2TSHRCA1 | |
| SCHEMBL12920544 | 0.79 | TSHR (0.58) | PRKCAAKT1PTK2TSHRCA1 | |
| Catechol SCHEMBL6657117 | 0.79 | TSHR (0.62) | PRKCAAKT1PTK2TSHRCA1 | |
| SCHEMBL10495769 | 0.79 | TSHR (0.57) | TSHRCA1CA2CA9CA12 | |
| SCHEMBL10495776 | 0.79 | TSHR (0.57) | TSHRCA1CA2CA9CA12 | |
| SCHEMBL10495788 | 0.79 | TSHR (0.57) | TSHRCA1CA2CA9CA12 | |
| SCHEMBL12450812 | 0.78 | PTPN1 (0.56) | TSHRCA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830873-A | ANTIDIABETIC AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |