SCHEMBL8660409

SCHEMBL8660409

N#CC(C#N)c1ccccc1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
CYP2C19 P33261 2/20 0.42
ACP3 P15309 1/20 0.41
TSHR P16473 4/20 0.41
LMNA P02545 2/20 0.41
HIF1A Q16665 3/20 0.39
IDO1 P14902 2/20 0.39
TDO2 P48775 2/20 0.39
IDO2 Q6ZQW0 2/20 0.39
CYP2C9 P11712 1/20 0.39
KDM4E B2RXH2 1/20 0.39
NR1I2 O75469 1/20 0.39
ABCB11 O95342 1/20 0.39
NR3C1 P04150 1/20 0.39
PGR P06401 1/20 0.39
CYP3A4 P08684 1/20 0.39
ADRA2A P08913 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
MAPT P10636 1/20 0.39
CNR1 P21554 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30029908 1.00 ALDH1A1 (0.49) ALDH1A1CYP2C19ACP3TSHRLMNA
SCHEMBL10332219 0.82 TSHR (0.40) ALDH1A1TSHRLMNAL3MBTL1TRPA1
SCHEMBL9664891 0.81 ALDH1A1 (0.62) ALDH1A1CYP2C19ACP3TSHRLMNA
SCHEMBL1629226 0.79 ALDH1A1 (0.47) ALDH1A1CYP2C19ACP3TSHRLMNA
SCHEMBL2863135 0.77 ALDH1A1 (0.46) ALDH1A1CYP2C19ACP3TSHRLMNA
SCHEMBL194129 0.77 TSHR (0.50) ALDH1A1CYP2C19ACP3TSHRLMNA
SCHEMBL2245671 0.77 ALDH1A1 (0.46) ALDH1A1CYP2C19ACP3TSHRLMNA
SCHEMBL1628591 0.77 TRPA1 (0.50) ALDH1A1CYP2C19ACP3TSHRLMNA
SCHEMBL2163244 0.77 ALDH1A1 (0.46) ALDH1A1CYP2C19ACP3TSHRLMNA
SCHEMBL1628799 0.77 TSHR (0.50) ALDH1A1CYP2C19ACP3TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119701804-A Aerosol generating device utilizing air injection spraying and blowing principles and control method 中国人民解放军61699部队 2025-03-28 CN claimed
CN-118984653-A Vaporizable alkaloid compositions and methods of use thereof 瑞迪美天然有限公司 2024-11-19 CN claimed
CN-118670205-A Intensity polycarbonate board 瀚海新材料(南通)有限公司 2024-09-20 CN claimed
CN-116535368-A Dicyanomethane compound and synthesis method and application thereof 浙江理工大学嵊州创新研究院有限公司 2023-08-04 CN claimed
CN-115403623-A Method for preparing 2-pyrrolyl substituted phosphine oxide compound 湖南理工学院 2022-11-29 CN claimed
CN-119950500-A Tobacco pest-reducing and pain-relieving products and methods thereof 瑞迪美天然有限公司 2025-05-09 CN disclosed
CN-119908508-A Gasified alkaloid composition and method of use thereof 瑞迪美天然有限公司 2025-05-02 CN disclosed
CN-119523150-A Gasified alkaloid composition and method of use thereof 瑞迪美天然有限公司 2025-02-28 CN disclosed
CN-118984653-A Vaporizable alkaloid compositions and methods of use thereof 瑞迪美天然有限公司 2024-11-19 CN disclosed
CN-118670205-A Intensity polycarbonate board 瀚海新材料(南通)有限公司 2024-09-20 CN disclosed
CN-117683009-A Polysubstituted 4H-pyran derivative and preparation method thereof 郑州铁路职业技术学院 2024-03-12 CN disclosed
CN-117288044-A Gun barrel connecting device for transmitting hand-thrown antiriot bullets 中国人民解放军61699部队 2023-12-26 CN disclosed
CN-117109371-A Anti-riot stimulant aerosol generating device 中国人民解放军61699部队 2023-11-24 CN disclosed
US-9315792-B2 Nitrilases, nucleic acids encoding them and methods for making and using them BASF ENZYMES LLC (US) 2016-04-19 US disclosed
US-9315792-B2 Nitrilases, nucleic acids encoding them and methods for making and using them BASF ENZYMES LLC (US) 2016-04-19 US disclosed
US-20150125928-A1 NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM BASF ENZYMES LLC 2015-05-07 US disclosed
US-20150125928-A1 NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM BASF ENZYMES LLC 2015-05-07 US disclosed
EP-0714893-B1 2-substituted benzothiazole derivatives useful in the treatment of diabetic complications GRELAN PHARMACEUTICAL CO (JP) 1998-10-21 EP disclosed
US-5700819-A ALDOSE REDUCTASE ENZYME INHIBITOR GRELAN PHARMACEUTICAL CO., LTD. (JP) 1997-12-23 US disclosed
EP-0714893-A1 2-substituted benzothiazole derivatives useful in the treatment of diabetic complications GRELAN PHARMACEUTICAL CO., LTD. (JP) 1996-06-05 EP disclosed