SCHEMBL866041

SCHEMBL866041

COc1cc(N)c(Br)cc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.59
FYN P06241 1/20 0.59
ALDH1A1 P00352 5/20 0.56
ACHE P22303 3/20 0.55
CYP1A2 P05177 1/20 0.55
HTR1A P08908 1/20 0.55
ADRA2A P08913 1/20 0.55
CYP2D6 P10635 1/20 0.55
DRD1 P21728 1/20 0.55
PTGS1 P23219 1/20 0.55
DRD3 P35462 1/20 0.55
KDM4E B2RXH2 5/20 0.51
HPGD P15428 2/20 0.51
GAA P10253 1/20 0.47
HSD17B10 Q99714 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
POLB P06746 1/20 0.47
HTR4 Q13639 2/20 0.45
NPSR1 Q6W5P4 1/20 0.43
GLA P06280 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27685955 0.93 LCK (0.65) LCKFYNALDH1A1ACHECYP1A2
SCHEMBL1707143 0.87 LCK (0.58) LCKFYNALDH1A1ACHECYP1A2
SCHEMBL3343357 0.87 ACHE (0.53) LCKFYNALDH1A1ACHECYP1A2
SCHEMBL1965781 0.86 ALDH1A1 (0.61) LCKFYNALDH1A1KDM4EHPGD
SCHEMBL31634578 0.86 ALDH1A1 (0.61) LCKFYNALDH1A1KDM4EHPGD
SCHEMBL169553 0.86 GAA (0.66) LCKFYNALDH1A1ACHECYP1A2
SCHEMBL9706363 0.85 ALDH1A1 (0.59) LCKFYNALDH1A1KDM4EHPGD
Hydrochloric Acid SCHEMBL7410965 0.84 GAA (0.64) LCKFYNALDH1A1ACHECYP1A2
SCHEMBL16403724 0.84 ACHE (0.54) LCKFYNALDH1A1ACHECYP1A2
SCHEMBL5067150 0.83 HTT (0.55) LCKFYNALDH1A1ACHECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799791-B1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2016-01-13 EP claimed
US-7687118-B2 Photocrosslinkable materials ROLIC AG (CH) 2010-03-30 US claimed
US-20080069968-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-03-20 US claimed
EP-1799791-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2007-06-27 EP claimed
WO-2006039824-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2006-04-20 WO claimed
EP-4720038-A1 (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES Neophore Limited (GB) 2026-04-08 EP disclosed
US-20250180952-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-06-05 US disclosed
EP-4493638-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-01-22 EP disclosed
WO-2024246496-A1 (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES Neophore Limited (GB) 2024-12-05 WO disclosed
CN-118871548-A Photoalignment materials 罗利克技术有限公司 2024-10-29 CN disclosed
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
WO-2023174773-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2023-09-21 WO disclosed
US-4703055-A GASTROMOTOR AGENTS; NO SIDE EFFECTS SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) 1987-10-27 US disclosed
EP-0236646-A1 Ortho-anisamides, process for their preparation and their pharmaceutical applications Laboratoires DELAGRANGE, Société Anonyme (FR) 1987-09-16 EP disclosed
EP-0220011-A2 Use of azabicloalkylbenzamides in the treatment of gastrointestinal motility disorders, migraine, emesis, cluster headaches, trigeminal neuralgia and arrhythmia BEECHAM GROUP PLC (GB) 1987-04-29 EP disclosed
EP-0076592-B1 AZABICYCLO-(3,3,1)-NONYLBENZAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BEECHAM GROUP PLC (GB) 1987-01-28 EP disclosed
EP-0190915-A2 Process for the preparation of 2-alkoxy-N-(1-azabicyclo[2.2.2]octan-3-yl) aminobenzamides SYNTHELABO (FR) 1986-08-13 EP disclosed
US-4560757-A 9-Azabicyclo(3.3.1) nonane intermediates for compounds useful in the treatment of CNS disorders BEECHAM GROUP P.L.C. (GB) 1985-12-24 US disclosed
US-4472413-A PSYCHOLOGICAL DISORDERS BEECHAM GROUP P.L.C. (GB) 1984-09-18 US disclosed
EP-0076592-A2 Azabicyclo-(3,3,1)-nonylbenzamide derivatives, processes for their preparation, and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1983-04-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080069968-A1 Photocrosslinkable Materials PARG, VSIR, IGLV6-57 LCK 2717/4885FYN 4330/4885ALDH1A1 1606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.