Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | GNG2 | P59768 | 1/20 | 0.42 |
| ▸ | GNB1 | P62873 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20555452 | 0.92 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2D6GNG2GNB1 | |
| SCHEMBL14281484 | 0.87 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2D6GNG2GNB1 | |
| Sulfuric Acid SCHEMBL16728394 | 0.82 | APAF1 (0.48) | ENPP2ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL20969281 | 0.81 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2D6GNG2GNB1 | |
| SCHEMBL20969282 | 0.81 | KMT2A (0.46) | ALDH1A1CYP1A2CYP2D6GNG2GNB1 | |
| Hydrochloric Acid SCHEMBL20969312 | 0.81 | KMT2A (0.46) | ALDH1A1CYP1A2CYP2D6GNG2GNB1 | |
| Sulfuric Acid SCHEMBL519200 | 0.81 | ALDH1A1 (0.42) | ENPP2ALDH1A1CYP1A2CYP2D6GNG2 | |
| Sulfuric Acid SCHEMBL865288 | 0.80 | NPC1 (0.49) | ENPP2ALDH1A1CYP1A2CYP2D6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL15265 | 0.78 | NPC1 (0.47) | ALDH1A1L3MBTL1NPC1RAB9ANLRP3 | |
| SCHEMBL10005072 | 0.78 | ALDH1A1 (0.55) | ENPP2ALDH1A1CYP1A2CYP2D6GNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619244-B1 | IMPROVED METHOD OF PRODUCING POLYMERIC PHENAZONIUM COMPOUNDS | MACDERMID ACUMEN INC (US) | 2018-11-14 | — | — | EP | claimed |
| US-9040700-B2 | Method of producing polymeric phenazonium compounds | CITIBANK, N.A. | 2015-05-26 | — | — | US | claimed |
| US-20140163198-A1 | Method of Producing Polymeric Phenazonium Compounds | MACDERMID ACUMEN, INC. (US) | 2014-06-12 | — | — | US | claimed |
| US-8735580-B2 | Method of producing polymeric phenazonium compounds | CITIBANK, N.A. | 2014-05-27 | — | — | US | claimed |
| EP-2619244-A1 | IMPROVED METHOD OF PRODUCING POLYMERIC PHENAZONIUM COMPOUNDS | MacDermid Acumen, Inc. (US) | 2013-07-31 | — | — | EP | claimed |
| US-20120073981-A1 | Method of Producing Polymeric Phenazonium Compounds | CITIBANK, N.A. | 2012-03-29 | — | — | US | claimed |
| WO-2012040417-A1 | IMPROVED METHOD OF PRODUCING POLYMERIC PHENAZONIUM COMPOUNDS | MACDERMID ACUMEN, INC. (US) | 2012-03-29 | — | — | WO | claimed |
| EP-2619244-B1 | IMPROVED METHOD OF PRODUCING POLYMERIC PHENAZONIUM COMPOUNDS | MACDERMID ACUMEN INC (US) | 2018-11-14 | — | — | EP | disclosed |
| US-9040700-B2 | Method of producing polymeric phenazonium compounds | CITIBANK, N.A. | 2015-05-26 | — | — | US | disclosed |
| US-20140163198-A1 | Method of Producing Polymeric Phenazonium Compounds | MACDERMID ACUMEN, INC. (US) | 2014-06-12 | — | — | US | disclosed |
| US-8735580-B2 | Method of producing polymeric phenazonium compounds | CITIBANK, N.A. | 2014-05-27 | — | — | US | disclosed |
| EP-2619244-A1 | IMPROVED METHOD OF PRODUCING POLYMERIC PHENAZONIUM COMPOUNDS | MacDermid Acumen, Inc. (US) | 2013-07-31 | — | — | EP | disclosed |
| US-20120073981-A1 | Method of Producing Polymeric Phenazonium Compounds | CITIBANK, N.A. | 2012-03-29 | — | — | US | disclosed |
| US-20120077956-A1 | Method of Producing Polymeric Phenazonium Compounds | CITIBANK, N.A. | 2012-03-29 | — | — | US | disclosed |
| WO-2012040417-A1 | IMPROVED METHOD OF PRODUCING POLYMERIC PHENAZONIUM COMPOUNDS | MACDERMID ACUMEN, INC. (US) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120073981-A1 | Method of Producing Polymeric Phenazonium Compounds | NOX5, PRMT5, CHRM5 | ENPP2 2999/4885ALDH1A1 2815/4885CYP1A2 1412/4885 |
| US-20140163198-A1 | Method of Producing Polymeric Phenazonium Compounds | NOX5, PRMT5, H1-5 | ENPP2 2827/4885ALDH1A1 2671/4885CYP1A2 1668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.