Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659862 | 0.84 | KMT2A (0.38) | KMT2AELANEPRMT5WDR77BRD9 | |
| SCHEMBL8837511 | 0.83 | CXCL8 (0.49) | CXCL8ELANERXFP1BRD9 | |
| SCHEMBL1951665 | 0.83 | CXCL8 (0.49) | CXCL8ELANERXFP1BRD9 | |
| SCHEMBL1951582 | 0.83 | CXCL8 (0.49) | CXCL8ELANERXFP1BRD9 | |
| SCHEMBL8662469 | 0.82 | RAB9A (0.51) | KMT2AELANEALDH1A1TDP1 | |
| SCHEMBL8661782 | 0.80 | MAPK8 (0.47) | KMT2AALDH1A1 | |
| SCHEMBL8664717 | 0.79 | CXCL8 (0.43) | CXCL8ELANERXFP1BRD9 | |
| SCHEMBL8660694 | 0.76 | NPSR1 (0.48) | KMT2AELANERXFP1BRD9ALDH1A1 | |
| SCHEMBL8214432 | 0.75 | IDO1 (0.43) | CXCL8ELANERXFP1BRD9 | |
| SCHEMBL8462214 | 0.74 | PTGS1 (0.43) | KMT2ACXCL8ELANERXFP1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760251-A | Taxol process and compounds | SEPRACOR, INC. (US) | 1998-06-02 | — | — | US | disclosed |
| WO-1997007110-A1 | PROCESS FOR PRODUCING TAXOL DERIVATIVES AND INTERMEDIATES THEREFOR | SEPRACOR, INC. (US) | 1997-02-27 | — | — | WO | disclosed |