Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119253 | 0.92 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HSP90AA1MEN1KMT2A | |
| SCHEMBL8657124 | 0.85 | HSP90AA1 (0.67) | ALDH1A1HSP90AA1MEN1KMT2ANPSR1 | |
| SCHEMBL8654682 | 0.80 | HSP90AA1 (0.71) | ALDH1A1SMN1; SMN2HSP90AA1MEN1KMT2A | |
| SCHEMBL9120300 | 0.77 | CYP2C9 (0.57) | ALDH1A1SMN1; SMN2HSP90AA1MEN1KMT2A | |
| SCHEMBL9119844 | 0.75 | KMT2A (0.57) | ALDH1A1SMN1; SMN2HSP90AA1MEN1KMT2A | |
| SCHEMBL9117209 | 0.75 | HSP90AA1 (0.60) | ALDH1A1HSP90AA1MEN1KMT2ANPSR1 | |
| SCHEMBL9118627 | 0.75 | HSP90AA1 (0.54) | ALDH1A1HSP90AA1MEN1KMT2ANPSR1 | |
| SCHEMBL7770174 | 0.73 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2HSP90AA1MEN1KMT2A | |
| SCHEMBL9119962 | 0.72 | CYP2C9 (0.60) | ALDH1A1SMN1; SMN2HSP90AA1MEN1KMT2A | |
| SCHEMBL9119790 | 0.72 | KMT2A (0.54) | ALDH1A1SMN1; SMN2HSP90AA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617023-B1 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1998-10-21 | — | — | EP | disclosed |
| EP-0617023-A1 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1994-09-28 | — | — | EP | disclosed |