Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 2/20 | 0.89 |
| ▸ | LMNA | P02545 | 3/20 | 0.85 |
| ▸ | BLM | P54132 | 3/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.85 |
| ▸ | MAPT | P10636 | 1/20 | 0.85 |
| ▸ | RAB9A | P51151 | 1/20 | 0.85 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.85 |
| ▸ | ARG1 | P05089 | 3/20 | 0.66 |
| ▸ | ARG2 | P78540 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866087 | 1.00 | ODC1 (0.89) | ODC1LMNABLMKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL10999722 | 0.98 | BLM (0.89) | ODC1LMNABLMKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL11001948 | 0.98 | BLM (0.89) | ODC1LMNABLMKDM4EMAPT | |
| Eflornithine SCHEMBL26327 | 0.94 | ODC1 (1.00) | ODC1LMNABLMKDM4EMAPT | |
| Eflornithine SCHEMBL8581344 | 0.94 | ODC1 (1.00) | ODC1LMNABLMKDM4EMAPT | |
| D-Eflornithine SCHEMBL60699 | 0.94 | ODC1 (1.00) | ODC1LMNABLMKDM4EMAPT | |
| Eflornithine, (S)- SCHEMBL60698 | 0.94 | ODC1 (1.00) | ODC1LMNABLMKDM4EMAPT | |
| D-Eflornithine SCHEMBL3244719 | 0.92 | ODC1 (0.96) | ODC1LMNABLMKDM4EMAPT | |
| Eflornithine, (S)- SCHEMBL1322403 | 0.92 | BLM (1.00) | ODC1LMNABLMKDM4EMAPT | |
| Eflornithine SCHEMBL3244711 | 0.92 | ODC1 (0.96) | ODC1LMNABLMKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250197916-A1 | METHODS AND COMPOSITIONS FOR SUPPRESSION OF BIOGENIC AMINES PRODUCED BY THE GUT MICROBIOME | CEDARS-SINAI MEDICAL CENTER (US) | 2025-06-19 | — | — | US | claimed |
| US-20140255991-A1 | OVEREXPRESSION OF AMINOACYL-tRNA SYNTHETASES FOR EFFICIENT PRODUCTION OF ENGINEERED PROTEINS CONTAINING AMINO ACID ANALOGUES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-09-11 | — | — | US | claimed |
| US-20120077228-A1 | OVEREXPRESSION OF AMINOACYL-tRNA SYNTHETASES FOR EFFICIENT PRODUCTION OF ENGINEERED PROTEINS CONTAINING AMINO ACID ANALOGUES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-03-29 | — | — | US | claimed |
| US-20080160609-A1 | Dihydrofolate reductase; site directed mutagenesis; point mutations; auxotroph host cells | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-07-03 | — | — | US | claimed |
| US-6187296-B1 | SUCH AS ALPHA-DIFLUOROMETHYL LYSINE (DEML) OR ALPHA-MONOFLUOROMETHYL LYSINE (MFML) | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2001-02-13 | — | — | US | claimed |
| US-6103220-A | Lysine decarboxylase inhibitors for the prevention and treatment of periodontal disease | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2000-08-15 | — | — | US | claimed |
| US-4560795-A | α-Halomethyl derivatives of α-amino acids | Merrell Dow France et Cie. (FR) | 1985-12-24 | — | — | US | claimed |
| US-4496588-A | HALOMETHYL DERIVATIVES OF A-AMINO ACID | MERRELL TORAUDE ET COMPAGNIE (FR) | 1985-01-29 | — | — | US | claimed |
| US-20250197916-A1 | METHODS AND COMPOSITIONS FOR SUPPRESSION OF BIOGENIC AMINES PRODUCED BY THE GUT MICROBIOME | CEDARS-SINAI MEDICAL CENTER (US) | 2025-06-19 | — | — | US | disclosed |
| US-20250156160-A1 | SYSTEM AND METHOD FOR AUTOMATED MAPPING OF DATA TYPES FOR USE WITH DATAFLOW ENVIRONMENTS | ORACLE INTERNATIONAL CORPORATION | 2025-05-15 | — | — | US | disclosed |
| US-20250156160-A1 | SYSTEM AND METHOD FOR AUTOMATED MAPPING OF DATA TYPES FOR USE WITH DATAFLOW ENVIRONMENTS | ORACLE INTERNATIONAL CORPORATION | 2025-05-15 | — | — | US | disclosed |
| US-12282757-B2 | System and method for automated mapping of data types for use with dataflow environments | ORACLE INTERNATIONAL CORPORATION (US) | 2025-04-22 | — | — | US | disclosed |
| US-12282757-B2 | System and method for automated mapping of data types for use with dataflow environments | ORACLE INTERNATIONAL CORPORATION (US) | 2025-04-22 | — | — | US | disclosed |
| US-20250111889-A1 | DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES | UNIVERSITY OF WASHINGTON | 2025-04-03 | — | — | US | disclosed |
| US-4879223-A | Method for producing protein containing nonprotein amino acids | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0288087-A2 | Method for producing protein containing nonprotein amino acids | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1988-10-26 | — | — | EP | disclosed |
| US-4560795-A | α-Halomethyl derivatives of α-amino acids | Merrell Dow France et Cie. (FR) | 1985-12-24 | — | — | US | disclosed |
| US-4496588-A | HALOMETHYL DERIVATIVES OF A-AMINO ACID | MERRELL TORAUDE ET COMPAGNIE (FR) | 1985-01-29 | — | — | US | disclosed |
| US-4438270-A | DECARBOXYLASE INHIBITORS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-03-20 | — | — | US | disclosed |
| US-4405530-A | Process for preparing fluorinated amino-nitriles | MERRELL TORAUDE ET COMPAGNIE (FR) | 1983-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250111889-A1 | DE NOVO DESIGNED MACROCYCLIC OLIGOAMIDES | DHFR, CCNH, ODC1 | ODC1 3/4885LMNA 1387/4885BLM 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.