SCHEMBL8660922

SCHEMBL8660922

CON1C(=O)CCC(=O)[C@]1(C)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N([N+]=O)c1ccccc1)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ELANE P08246 19/20 0.39
EP300 Q09472 1/20 0.34
CREBBP Q92793 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8665933 0.92 EP300 (0.37) ELANEEP300CREBBP
SCHEMBL5494650 0.91 ELANE (0.40) ELANE
SCHEMBL7410732 0.77 ELANE (0.43) ELANE
SCHEMBL7400531 0.77 ELANE (0.47) ELANE
SCHEMBL10895690 0.76 ELANE (0.42) ELANE
SCHEMBL2289363 0.73 ELANE (0.42) ELANE
SCHEMBL8663260 0.73 ELANE (0.32) ELANE
SCHEMBL8662695 0.73 ELANE (0.45) ELANE
SCHEMBL8662040 0.71 ELANE (0.40) ELANE
SCHEMBL847832 0.70 CMA1 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776780-A AUTOMATIC ANALYZING; COLORIMETRIC PHOTOMETRY CHIMERA RESEARCH & CHEMICAL, INC. (US) 1998-07-07 US claimed