Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 17/20 | 0.47 |
| ▸ | XIAP | P98170 | 2/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662695 | 0.86 | ELANE (0.45) | ELANEXIAPCTSGMLX | |
| SCHEMBL7351756 | 0.85 | TACR1 (0.52) | SLC6A2 | |
| SCHEMBL7410732 | 0.83 | ELANE (0.43) | ELANEXIAPMLX | |
| SCHEMBL8182012 | 0.82 | ACE (0.44) | — | |
| SCHEMBL10895690 | 0.79 | ELANE (0.42) | ELANE | |
| SCHEMBL7213508 | 0.78 | TACR1 (0.49) | XIAPSLC6A2 | |
| SCHEMBL29758603 | 0.78 | XIAP (0.62) | ELANEXIAP | |
| SCHEMBL5494650 | 0.77 | ELANE (0.40) | ELANEXIAPMLX | |
| SCHEMBL8660922 | 0.77 | ELANE (0.39) | ELANE | |
| SCHEMBL24056573 | 0.76 | CFD (0.56) | XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212300-A1 | AZACYCLOALKANONE SERINE PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001019795-A1 | AZACYCLOALKANONE SERINE PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | disclosed |