Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | XIAP | P98170 | 12/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578666 | 0.91 | GHSR (0.43) | GHSRAGTR1XIAP | |
| SCHEMBL8578667 | 0.90 | GHSR (0.42) | GHSRAGTR1XIAP | |
| SCHEMBL8578662 | 0.90 | GHSR (0.42) | GHSRAGTR1XIAP | |
| SCHEMBL8713087 | 0.90 | GHSR (0.42) | GHSRAGTR1XIAPPSEN1PSEN2 | |
| SCHEMBL8523460 | 0.82 | AGTR1 (0.53) | GHSRAGTR1XIAP | |
| Hydrochloric Acid SCHEMBL8714288 | 0.81 | AGTR1 (0.52) | GHSRAGTR1XIAP | |
| SCHEMBL8523099 | 0.81 | GHSR (0.61) | GHSRAGTR1XIAP | |
| SCHEMBL14977965 | 0.81 | GHSR (0.61) | GHSRAGTR1XIAP | |
| Trifluoroacetic Acid SCHEMBL8716938 | 0.77 | GHSR (0.57) | GHSRAGTR1XIAPPSEN1PSEN2 | |
| SCHEMBL8717060 | 0.76 | GHSR (0.54) | GHSRAGTR1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817654-A | STIMULATE GROWTH HORMONES | NOVO NORDISK A/S (DK) | 1998-10-06 | — | — | US | claimed |
| EP-0907374-A1 | GROWTH HORMONE COMPONENT AND BONE ANTI-RESORPTIVE AGENT IN CYCLIC (COHERENCE) TREATMENT OF OSTEOPOROSIS | NOVO NORDISK A/S (DK) | 1999-04-14 | — | — | EP | disclosed |
| US-5817654-A | STIMULATE GROWTH HORMONES | NOVO NORDISK A/S (DK) | 1998-10-06 | — | — | US | disclosed |
| WO-1997046252-A1 | GROWTH HORMONE COMPONENT AND BONE ANTI-RESORPTIVE AGENT IN CYCLIC (COHERENCE) TREATMENT OF OSTEOPOROSIS | NOVO NORDISK A/S (DK) | 1997-12-11 | — | — | WO | disclosed |
| EP-0777668-A1 | NOVEL N-SUBSTITUTED NAPHTHOFUSED LACTAMS | NOVO NORDISK A/S (DK) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005195-A1 | NOVEL N-SUBSTITUTED NAPHTHOFUSED LACTAMS | NOVO NORDISK A/S (DK) | 1996-02-22 | — | — | WO | disclosed |