Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 11/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662513 | 0.89 | MEN1 (0.45) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL9135451 | 0.86 | MEN1 (0.41) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8659833 | 0.85 | PYGL (0.47) | MEN1KMT2ASCN9APOLBNPC1 | |
| SCHEMBL8666686 | 0.84 | KMT2A (0.43) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL9135334 | 0.84 | KMT2A (0.51) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8089012 | 0.84 | MEN1 (0.51) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8660055 | 0.83 | KMT2A (0.53) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8657776 | 0.82 | KMT2A (0.51) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8663112 | 0.82 | MEN1 (0.41) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8659428 | 0.82 | KMT2A (0.53) | MEN1KMT2AMAPTUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |