Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 11/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135451 | 0.97 | MEN1 (0.41) | MEN1KMT2AMETMAPTUSP2 | |
| SCHEMBL8655814 | 0.92 | TAS1R3 (0.38) | MEN1KMT2AMAPTSCN9AKDM4E | |
| SCHEMBL8660997 | 0.89 | MEN1 (0.48) | MEN1KMT2AMETMAPTUSP2 | |
| SCHEMBL8659922 | 0.88 | MET (0.42) | MEN1KMT2AMETMAPTUSP2 | |
| SCHEMBL8663086 | 0.87 | MEN1 (0.43) | MEN1KMT2AMETMAPTUSP2 | |
| SCHEMBL8658220 | 0.86 | PYGL (0.43) | SCN9APOLBNPC1TDP1 | |
| SCHEMBL8658809 | 0.85 | KDM4E (0.43) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8656206 | 0.85 | KDM4E (0.46) | MEN1KMT2AMETMAPTSCN9A | |
| SCHEMBL10639071 | 0.83 | MEN1 (0.43) | MEN1KMT2AMETMAPTUSP2 | |
| SCHEMBL8656628 | 0.83 | MEN1 (0.45) | MEN1KMT2AMAPTUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0115210-B1 | PESTICIDAL BENZOYL UREAS AND PROCESS FOR THEIR PREPARATION | UNION CARBIDE CORPORATION (US) | 1988-05-11 | — | — | EP | disclosed |
| US-4659724-A | Certain 1-[4-(5-cyano-2-pyridyloxy)phenyl-benzoyl ureas having pesticidal properties | UNION CARBIDE CORPORATION (US) | 1987-04-21 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| EP-0115210-A1 | Pesticidal benzoyl ureas and process for their preparation | UNION CARBIDE CORPORATION (US) | 1984-08-08 | — | — | EP | disclosed |