Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GCGR | P47871 | 1/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.46 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.46 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658849 | 0.90 | TLR8 (0.56) | TDP1TLR8TLR7BRAFKDR | |
| SCHEMBL8662619 | 0.86 | TLR8 (0.59) | TLR8TLR7BRAFKDRALDH1A1 | |
| SCHEMBL8661106 | 0.86 | GCGR (0.64) | TDP1GCGRAVPR2GPR27 | |
| SCHEMBL8662540 | 0.86 | TDP1 (0.59) | TDP1GCGRTLR8TLR7RORC | |
| SCHEMBL8659897 | 0.84 | GCGR (0.72) | TDP1GCGRTLR8TLR7RORC | |
| SCHEMBL9325879 | 0.83 | GCGR (0.69) | TDP1GCGRTLR8TLR7RORC | |
| SCHEMBL8656699 | 0.81 | GCGR (0.56) | TDP1GCGRPCTPALDH1A1HTT | |
| Chlotrifmeuron SCHEMBL10868747 | 0.79 | TDP1 (0.70) | TDP1GCGRRORCPCTPPLCG2 | |
| SCHEMBL8658915 | 0.78 | TLR8 (0.57) | TLR8TLR7ALDH1A1HTTLMNA | |
| SCHEMBL15171164 | 0.77 | RORC (0.66) | TDP1TLR8TLR7RORCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |