SCHEMBL8661402

SCHEMBL8661402

CCOC(OCC)(OCC)C(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.43
HDAC6 Q9UBN7 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA7 P43166 1/20 0.32
CA14 Q9ULX7 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
CYP4F2 P78329 2/20 0.31
CYP4A11 Q02928 2/20 0.31
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27665143 0.81 DGAT1 (0.43) DGAT1HDAC6CA12CA1CA7
SCHEMBL17486950 0.81 DGAT1 (0.43) DGAT1HDAC6CA12CA1CA7
SCHEMBL3393438 0.77 DGAT1 (0.40) DGAT1HDAC6CA12CA1CA7
SCHEMBL788715 0.75 ALDH1A1 (0.46) CYP4F2CYP4A11ALDH1A1
SCHEMBL15951338 0.75 MGAM (0.36) DGAT1ALDH1A1
SCHEMBL5702342 0.73 CYP4F2 (0.35) CYP4F2CYP4A11ALDH1A1
SCHEMBL5936809 0.73 ALDH1A1 (0.43) CYP4F2CYP4A11ALDH1A1
SCHEMBL28907069 0.73 CYP2D6 (0.33) DGAT1CA12CA1CA7CA14
SCHEMBL5682370 0.73 DGAT1 (0.41) DGAT1CA12CA1CA7CA14
SCHEMBL28513604 0.73 CYP2D6 (0.33) DGAT1CA12CA1CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5780673-A REACTING 1,1-DIFLUOROTETRAHALOETHANE WITH ALCOHOL IN PRESENCE OF OXYGEN AND FREE RADICAL INITIATOR ELF ATOCHEM S.A. (FR) 1998-07-14 US disclosed
CN-1169419-A Process for preparation of alkyl halodifluoroacetates ATOCHEM ELF SA (FR) 1998-01-07 CN disclosed
US-5619023-A Process for the preparation of alkyl halodifluoroacetates ELF ATOCHEM S.A. (FR) 1997-04-08 US disclosed
CN-1131659-A Process for preparation of alkyl halodifluoroacetates ATOCHEM ELF SA (FR) 1996-09-25 CN disclosed