Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486950 | 0.77 | DGAT1 (0.43) | DGAT1CA12CA1CA7CA14 | |
| SCHEMBL8661402 | 0.77 | DGAT1 (0.43) | DGAT1CA12CA1CA7CA14 | |
| SCHEMBL27665143 | 0.77 | DGAT1 (0.43) | DGAT1CA12CA1CA7CA14 | |
| SCHEMBL7098775 | 0.74 | ALOX15 (0.41) | DGAT1ALOX15 | |
| SCHEMBL5682370 | 0.74 | DGAT1 (0.41) | DGAT1CA12CA1CA7CA14 | |
| SCHEMBL1115801 | 0.73 | DGAT1 (0.43) | DGAT1CA12CA1CA7CA14 | |
| SCHEMBL14485421 | 0.73 | DGAT1 (0.48) | DGAT1CA12CA1CA7CA14 | |
| SCHEMBL12860069 | 0.73 | DGAT1 (0.48) | DGAT1CA12CA1CA7CA14 | |
| SCHEMBL14485423 | 0.73 | DGAT1 (0.48) | DGAT1CA12CA1CA7CA14 | |
| SCHEMBL8489844 | 0.73 | DGAT1 (0.43) | DGAT1CA12CA1CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673113-B1 | IMPLANTS WITH ATTACHED SILYLATED THERAPEUTIC AGENTS | SMART TECH LP (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20060286140-A1 | Implants with attached silylated therapeutic agents | SMART TECH LP | 2006-12-21 | — | — | US | disclosed |
| EP-1673113-A2 | IMPLANTS WITH ATTACHED SILYLATED THERAPEUTIC AGENTS | Wickstrom, Eric (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005027990-A2 | IMPLANTS WITH ATTACHED SILYLATED THERAPEUTIC AGENTS | UNIV JEFFERSON (US) | 2005-03-31 | — | — | WO | disclosed |