⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827285 | 0.84 | ALDH1A1 (0.32) | — | |
| SCHEMBL126792 | 0.84 | ALDH1A1 (0.32) | — | |
| SCHEMBL813378 | 0.84 | ALDH1A1 (0.32) | — | |
| SCHEMBL18177797 | 0.81 | ALDH1A1 (0.39) | — | |
| SCHEMBL1192112 | 0.81 | — | — | |
| SCHEMBL17058730 | 0.81 | — | — | |
| SCHEMBL5639003 | 0.81 | — | — | |
| Ethylene Glycol Diformate SCHEMBL827902 | 0.80 | — | — | |
| SCHEMBL4504041 | 0.79 | CYP3A4 (0.31) | — | |
| SCHEMBL514889 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756737-A | Process for the preparation of 9-(2-hydroxy)-ethoxymethyl-guanine | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1998-05-26 | — | — | US | disclosed |
| EP-0717744-B1 | A PROCESS FOR THE PREPARATION OF 9-(2-HYDROXY)-ETHOXYMETHYL-GUANINE | RECORDATI CHEM PHARM (CH) | 1997-05-07 | — | — | EP | disclosed |
| EP-0717744-A1 | A PROCESS FOR THE PREPARATION OF 9-(2-HYDROXY)-ETHOXYMETHYL-GUANINE | RECORDATI CHEM PHARM (CH) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007281-A1 | A PROCESS FOR THE PREPARATION OF 9-(2-HYDROXY)-ETHOXYMETHYL-GUANINE | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1995-03-16 | — | — | WO | disclosed |