Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514889 | 0.95 | — | — | |
| SCHEMBL18159938 | 0.91 | HSD17B10 (0.30) | HSD17B10 | |
| SCHEMBL4397692 | 0.85 | — | — | |
| SCHEMBL5401232 | 0.85 | CYP3A4 (0.33) | CYP3A4TSHRHSD17B10 | |
| SCHEMBL4396233 | 0.85 | CYP3A4 (0.33) | CYP3A4TSHRHSD17B10 | |
| SCHEMBL18177797 | 0.83 | ALDH1A1 (0.39) | TSHR | |
| SCHEMBL513840 | 0.81 | — | — | |
| SCHEMBL8661663 | 0.79 | — | — | |
| SCHEMBL3110362 | 0.79 | CES2 (0.42) | TSHR | |
| SCHEMBL1192112 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498350-B2 | Oxazolidinones as antibacterial agents | ASTRAZENECA AB (SE) | 2009-03-03 | — | — | US | disclosed |
| US-20060116386-A1 | Oxazolidinones as antibacterial agents | ASTRAZENECA AB (SE) | 2006-06-01 | — | — | US | disclosed |
| US-20060116389-A1 | Antibacterial oxazolidinones | ASTRA ZENECA AB (SE) | 2006-06-01 | — | — | US | disclosed |
| US-20060058317-A1 | Oxazolidinone derivatives as antibacterial | ASTRAZENECA AB (SE) | 2006-03-16 | — | — | US | disclosed |
| US-20060052399-A1 | Oxazolidinone derivatives as antibacterial agents | ASTRAZENECA AB (SE) | 2006-03-09 | — | — | US | disclosed |
| EP-1581524-A2 | OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | AstraZeneca AB (SE) | 2005-10-05 | — | — | EP | disclosed |
| EP-1575945-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIBACTERIAL | Astrazeneca AB (SE) | 2005-09-21 | — | — | EP | disclosed |
| EP-1575944-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIBACTERIAL AGENTS | Astrazeneca AB (SE) | 2005-09-21 | — | — | EP | disclosed |
| EP-1572687-A1 | ANTIBACTERIAL OXAZOLIDINONES | AstraZeneca AB (SE) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056819-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2004-07-08 | — | — | WO | disclosed |
| WO-2004056818-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIBACTERIAL | ASTRAZENECA AB (SE) | 2004-07-08 | — | — | WO | disclosed |
| WO-2004056816-A1 | ANTIBACTERIAL OXAZOLIDINONES | ASTRAZENECA AB (SE) | 2004-07-08 | — | — | WO | disclosed |
| WO-2004048350-A2 | OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2004-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116386-A1 | Oxazolidinones as antibacterial agents | MRPL21, MRPS23, DPP3 | CYP3A4 1089/4885TSHR 350/4885HSD17B10 692/4885 |
| US-20060058317-A1 | Oxazolidinone derivatives as antibacterial | MRPL21, XDH, PM20D2 | CYP3A4 732/4885TSHR 1282/4885HSD17B10 232/4885 |
| US-20060052399-A1 | Oxazolidinone derivatives as antibacterial agents | H1-3, MRPL21, ATAD3B | CYP3A4 1276/4885TSHR 1628/4885HSD17B10 166/4885 |
| US-20060116389-A1 | Antibacterial oxazolidinones | MRPL21, WIZ, NRDC | CYP3A4 946/4885TSHR 960/4885HSD17B10 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.