Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 3/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.45 |
| ▸ | RORA | P35398 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656754 | 0.90 | PGR (0.48) | KAT6APGRFFAR4MEN1KMT2A | |
| SCHEMBL8661357 | 0.86 | STAT3 (0.53) | KAT6APGRKEAP1NFE2L2FFAR4 | |
| SCHEMBL8659718 | 0.84 | KAT6A (0.54) | KAT6APGRFFAR4TSHRNPSR1 | |
| SCHEMBL8662846 | 0.83 | MCL1 (0.55) | KAT6AFFAR4TSHRNPSR1MEN1 | |
| SCHEMBL8658453 | 0.82 | CA12 (0.51) | KEAP1NFE2L2PKMMEN1KMT2A | |
| SCHEMBL8659865 | 0.82 | KAT6A (0.45) | KAT6AFFAR4PKMMEN1KMT2A | |
| SCHEMBL8656118 | 0.82 | PGR (0.52) | KAT6APGR | |
| SCHEMBL8660003 | 0.81 | ALDH1A1 (0.49) | KAT6AKMT2A | |
| SCHEMBL8661766 | 0.81 | PTGS2 (0.48) | PKMKMT2A | |
| SCHEMBL8659244 | 0.81 | ALDH1A1 (0.46) | KAT6AKEAP1NFE2L2FFAR4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |