Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607718 | 0.85 | MCHR1 (0.47) | ALDH1A1HSD17B10MCHR1CA12CA1 | |
| SCHEMBL8615201 | 0.85 | MCHR1 (0.47) | ALDH1A1HSD17B10MCHR1CA12CA1 | |
| SCHEMBL8103747 | 0.83 | MCHR1 (0.48) | ALDH1A1HSD17B10MCHR1CA12CA1 | |
| SCHEMBL8096814 | 0.83 | CA12 (0.47) | ALDH1A1HSD17B10MCHR1CA12CA1 | |
| SCHEMBL8089857 | 0.82 | NPSR1 (0.47) | HSD17B10MCHR1CA12CA1CA2 | |
| SCHEMBL6203746 | 0.80 | NOTUM (0.51) | ALDH1A1MCHR1CA12CA1CA2 | |
| SCHEMBL7613749 | 0.79 | MCHR1 (0.50) | ALDH1A1MCHR1CA12CA1CA2 | |
| SCHEMBL8103674 | 0.78 | MCHR1 (0.45) | HSD17B10MCHR1CA12CA1CA2 | |
| SCHEMBL8096830 | 0.78 | MCHR1 (0.44) | ALDH1A1HSD17B10MCHR1CA12CA1 | |
| SCHEMBL9201870 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HSD17B10HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828710-A1 | PROCESS FOR THE PREPARATION OF (THIO-)CARBONIC/CARBAMIC ACID 2-PYRROLIDONYL-3-ESTERS, THIO ESTERS AND AMIDES | ZENECA LIMITED (GB) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037466-A1 | PROCESS FOR THE PREPARATION OF (THIO-)CARBONIC/CARBAMIC ACID 2-PYRROLIDONYL-3-ESTERS, THIO ESTERS AND AMIDES | ZENECA LIMITED (GB) | 1996-11-28 | — | — | WO | disclosed |