Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661980 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HDAC3HDAC1HDAC2 | |
| SCHEMBL27482279 | 0.69 | MEN1 (0.46) | ALDH1A1HTR7CCR2HTR2C | |
| SCHEMBL8090603 | 0.69 | LMNA (0.43) | ALDH1A1HSD17B10POLBLMNA | |
| SCHEMBL8089983 | 0.67 | CA12 (0.38) | ALDH1A1POLBDRD2DRD3LMNA | |
| SCHEMBL27881749 | 0.67 | GFER (0.61) | ALDH1A1HTR7POLB | |
| SCHEMBL8885544 | 0.67 | LMNA (0.40) | ALDH1A1HSD17B10POLBCCR2LMNA | |
| SCHEMBL27519301 | 0.67 | HTR7 (0.42) | ALDH1A1HTR7POLBCCR2 | |
| SCHEMBL9201878 | 0.66 | HDAC3 (0.41) | ALDH1A1HDAC3HDAC1HDAC2POLB | |
| SCHEMBL8103220 | 0.66 | GFER (0.63) | ALDH1A1HTR7POLB | |
| SCHEMBL15682958 | 0.65 | FAAH (0.67) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |